Immunological synapse

Term · Chemistry · MLC-T-CHM-005687

The specialized interface formed at the point of contact between a lymphocyte, such as a T cell, and an antigen-presenting cell (APC). This highly organized structure involves the clustering of T-cell receptors, co-receptors, and adhesion molecules, facilitating stable cell-to-cell communication. The synapse structure is typically organized into a central supramolecular activation cluster (cSMAC) surrounded by a peripheral SMAC.

Table 1. Record
Identifier	MLC-T-CHM-005687
Field	Chemistry
Subject	Chemistry and Human Health
References	PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1189 (https://doi.org/10.1351/PAC-REC-11-06-03)
See also	T lymphocyte; T-cell receptor; Adhesion molecule; Antigen-presenting cell; Lipid raft; Major histocompatibility complex molecule

Record as JSON

{
  "id": "MLC-T-CHM-005687",
  "term": "Immunological synapse",
  "field": "Chemistry",
  "definition": "The specialized interface formed at the point of contact between a lymphocyte, such as a T cell, and an antigen-presenting cell (APC). This highly organized structure involves the clustering of T-cell receptors, co-receptors, and adhesion molecules, facilitating stable cell-to-cell communication. The synapse structure is typically organized into a central supramolecular activation cluster (cSMAC) surrounded by a peripheral SMAC.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte",
    "T-cell receptor",
    "adhesion molecule",
    "antigen-presenting cell",
    "lipid raft",
    "major histocompatibility complex molecule"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1189 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/immunological-synapse/"
}

Record 6,034 of 13,678 in Chemistry terminology (MLC-0109). Request the full dataset.