Pre-association

{
  "id": "MLC-T-CHM-009342",
  "term": "Pre-association",
  "field": "Chemistry",
  "definition": "The formation of a weakly bound complex between reactants before the actual chemical transformation occurs. This initial association is often driven by non-covalent interactions, such as van der Waals forces or hydrogen bonding. The pre-associated complex can then proceed to form products or dissociate back into reactants.",
  "subject": "Organic and Biomolecular Chemistry",
  "see_also": [
    "association",
    "molecularity",
    "chemical species",
    "diffusion",
    "encounter complex",
    "microscopic diffusion control",
    "molecular entity",
    "reaction path",
    "spectator mechanism",
    "stepwise reaction"
  ],
  "references": [
    "PAC, 1994, 66, 1077. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)' on page 1152 (https://doi.org/10.1351/pac199466051077)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/pre-association/"
}