pre-T cell

{
  "id": "MLC-T-CHM-009416",
  "term": "pre-T cell",
  "field": "Chemistry",
  "definition": "An immature T lymphocyte that has successfully rearranged its T cell receptor beta chain gene and expresses a pre-T cell receptor on its surface. These cells reside in the thymus and undergo further development, including the rearrangement of the alpha chain gene. They are characterized by the co-expression of CD4 and CD8 coreceptors.",
  "synonyms": [
    "single-positive cell",
    "thymocyte"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "CD4",
    "CD8",
    "T lymphocyte",
    "T-cell receptor",
    "cytotoxic T lymphocyte",
    "double-positive cell",
    "helper T lymphocyte",
    "autoantigen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1233 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/pre-t-cell/"
}