Immature
Term · Chemistry · MLC-T-CHM-005614
Describing a cell, particularly a lymphocyte, that has not yet fully differentiated to its final functional state. Immature B lymphocytes and T lymphocytes, for example, have rearranged their antigen receptor genes but have not yet been selected for survival and maturation in the bone marrow or thymus, respectively. These cells are not yet competent to mount a full immune response upon encountering an antigen.
| Identifier | MLC-T-CHM-005614 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1182 (https://doi.org/10.1351/PAC-REC-11-06-03) |
| See also | B lymphocyte; Peyer’s patch; T lymphocyte; Bone marrow; Lymph node; Lymphatic system; Primary lymphoid organ; Secondary lymphoid tissue; Spleen |
Record as JSON
{
"id": "MLC-T-CHM-005614",
"term": "Immature",
"field": "Chemistry",
"definition": "Describing a cell, particularly a lymphocyte, that has not yet fully differentiated to its final functional state. Immature B lymphocytes and T lymphocytes, for example, have rearranged their antigen receptor genes but have not yet been selected for survival and maturation in the bone marrow or thymus, respectively. These cells are not yet competent to mount a full immune response upon encountering an antigen.",
"subject": "Chemistry and Human Health",
"see_also": [
"B lymphocyte",
"Peyer’s patch",
"T lymphocyte",
"bone marrow",
"lymph node",
"lymphatic system",
"primary lymphoid organ",
"secondary lymphoid tissue",
"spleen"
],
"references": [
"PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1182 (https://doi.org/10.1351/PAC-REC-11-06-03)"
],
"url": "https://mlchart.com/terminology/chemistry/immature/"
}
Record 5,956 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.