B7 molecule

{
  "id": "MLC-T-CHM-001063",
  "term": "B7 molecule",
  "field": "Chemistry",
  "definition": "A family of co-stimulatory molecules expressed on antigen-presenting cells that interact with receptors on T lymphocytes to regulate immune responses. These interactions provide the second signal required for full T-cell activation, preventing anergy. CD80 (B7-1) and CD86 (B7-2) are the two primary B7 molecules that bind to CD28 on T cells.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "co-stimulation",
    "T lymphocyte",
    "lymphocyte activation",
    "antigen-presenting cell",
    "cytotoxic T lymphocyte antigen 4",
    "major histocompatibility complex",
    "immunological tolerance"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1132 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/b7-molecule/"
}