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Testicular feminization

Term · Chemistry · MLC-T-CHM-011892

A genetic condition, also known as androgen insensitivity syndrome, in which individuals who are genetically male (XY chromosomes) are resistant to male hormones (androgens). This resistance results in the development of female external genitalia, despite the presence of testes. The testes are typically located in the abdomen or inguinal canal.

Table 1. Record
IdentifierMLC-T-CHM-011892
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 812 (https://doi.org/10.1515/pac-2015-1202)
See alsoAbdominal cavity; Amenorrhea; Androgen receptor; Androgen; Genitalia; Karyotype; Masculinization; Pseudohermaphrodite; Secondary sexual characteristic; Testis
Record as JSON
{
  "id": "MLC-T-CHM-011892",
  "term": "Testicular feminization",
  "field": "Chemistry",
  "definition": "A genetic condition, also known as androgen insensitivity syndrome, in which individuals who are genetically male (XY chromosomes) are resistant to male hormones (androgens). This resistance results in the development of female external genitalia, despite the presence of testes. The testes are typically located in the abdomen or inguinal canal.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "abdominal cavity",
    "amenorrhea",
    "androgen receptor",
    "androgen",
    "genitalia",
    "karyotype",
    "masculinization",
    "pseudohermaphrodite",
    "secondary sexual characteristic",
    "testis"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 812 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/testicular-feminization/"
}

Record 12,684 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.