Triple screen

{
  "id": "MLC-T-CHM-012292",
  "term": "Triple screen",
  "field": "Chemistry",
  "definition": "A prenatal diagnostic test performed during the second trimester of pregnancy to assess the risk of certain chromosomal abnormalities and neural tube defects in the fetus. It measures the levels of three specific substances in the mother's blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3). Abnormal results indicate a need for further diagnostic testing.",
  "synonyms": [
    "triple test"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "alpha-fetoprotein",
    "chromosomal abnormality",
    "estriol",
    "fetus",
    "chorionic gonadotropin",
    "neural tube defect",
    "pregnancy",
    "trimester"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 815 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/triple-screen/"
}