Antinuclear antibody

{
  "id": "MLC-T-CHM-000702",
  "term": "Antinuclear antibody",
  "field": "Chemistry",
  "definition": "An autoantibody that targets components within the nucleus of a cell. These antibodies are produced by the immune system and can bind to nuclear antigens such as DNA, RNA, and proteins. The presence of antinuclear antibodies is a hallmark of systemic autoimmune diseases like systemic lupus erythematosus.",
  "synonyms": [
    "antinuclear factor (ANF)"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Sjögren syndrome",
    "autoimmune disease",
    "autoimmunity",
    "immune system",
    "mixed connective tissue disease",
    "rheumatoid arthritis",
    "scleroderma",
    "systemic lupus erythematosus"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1127 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/antinuclear-antibody/"
}