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Myeloperoxidase

Term · Chemistry · MLC-T-CHM-007733

A heme-containing enzyme found primarily in the azurophilic granules of neutrophils and monocytes. It catalyzes the formation of hypochlorous acid (HOCl) from hydrogen peroxide and chloride ions, a potent antimicrobial agent. This enzyme is a key component of the innate immune system's defense against pathogens.

Table 1. Record
IdentifierMLC-T-CHM-007733
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1217 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoGoodpasture syndrome; Wegener granulomatosis; Antineutrophil cytoplasmic autoantibody; Autoantibody; Autoimmune disease; Glomerulonephritis; Neutrophil
Record as JSON
{
  "id": "MLC-T-CHM-007733",
  "term": "Myeloperoxidase",
  "field": "Chemistry",
  "definition": "A heme-containing enzyme found primarily in the azurophilic granules of neutrophils and monocytes. It catalyzes the formation of hypochlorous acid (HOCl) from hydrogen peroxide and chloride ions, a potent antimicrobial agent. This enzyme is a key component of the innate immune system's defense against pathogens.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Goodpasture syndrome",
    "Wegener granulomatosis",
    "antineutrophil cytoplasmic autoantibody",
    "autoantibody",
    "autoimmune disease",
    "glomerulonephritis",
    "neutrophil"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1217 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/myeloperoxidase/"
}

Record 8,202 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.