Reciprocal mesenchymal-epithelial interaction

{
  "id": "MLC-T-CHM-013485",
  "term": "Reciprocal mesenchymal-epithelial interaction",
  "field": "Chemistry",
  "definition": "A continuous, bidirectional signaling process between mesenchymal cells and adjacent epithelial cells that directs their proliferation, differentiation, and morphogenesis during embryonic development. These interactions involve the exchange of growth factors and other signaling molecules that regulate gene expression in both cell types. This signaling is required for the proper formation of many organs, including the lungs, kidneys, and skin.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "epithelial-to-mesenchymal transition",
    "epithelium",
    "mesenchymal-to-epithelial transition",
    "mesenchyme",
    "paracrine",
    "prostate",
    "stromal cell",
    "urogenital sinus"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 799 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/reciprocal-mesenchymal-epithelial-interaction/"
}