Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: E (774)

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• ER positiveDescribes cells that have a protein that binds to the hormone estrogen. Cancer cells that are ER positive may...
• ERa36 Modulator IcaritinA metabolite of icariin, a principal flavonoid glycoside in Herba Epimedii (a traditional Chinese medicine...
• ERA-923A substance that is being studied as a treatment for cancer. It belongs to a family of drugs called...
• eragidomideA modulator of cereblon (CRBN), which is part of the cullin 4-RING E3 ubiquitin ligase complex (CRL4-CRBN E3...
• eramkafusp alfaA humanized monoclonal antibody directed against the human B-cell-specific cell surface antigen CD20 and...
• erastin analogue PRLX 93936A structural analogue of erastin with potential antineoplastic activity. Erastin analogue PRLX 93936 appears...
• erb-38 immunotoxinA toxic substance linked to an antibody that attaches to tumor cells and kills them.
• ErbB1A protein found on certain types of cells that binds to a substance called epidermal growth factor. The ErbB1...
• ERBB1 geneA gene that makes a protein that is involved in cell growth and cell survival. Mutated (changed) forms of the...
• ErbituxA drug used alone or with other drugs to treat certain types of head and neck cancer and colorectal cancer...
• ERCC2 geneA gene that makes a protein involved in the first step of making proteins and in repairing damaged DNA...
• ERCC3 geneA gene that makes a protein involved in the first step of making proteins and in repairing damaged DNA...
• ERCC4 geneA gene that makes a protein involved in repairing damaged DNA. Mutations (changes) in the ERCC4 gene may...
• ERCC5 geneA gene that makes a protein involved in repairing damaged DNA. Mutations (changes) in the ERCC5 gene may...
• ERCPA procedure that uses an endoscope to examine and x-ray the pancreatic duct, hepatic duct, common bile duct...
• erdafitinibA drug used to treat adults with urothelial cancer (a type of bladder or urinary tract cancer) that has...
• erdafitinib-releasing intravesical system TAR-210A controlled-release intravesical system consisting of a pretzel-shaped tube releasing erdafitinib, a pan...
• Erdheim-Chester diseaseA very rare disorder in which too many histiocytes (a type of white blood cell) build up in certain tissues...
• erectile dysfunctionAn inability to have an erection of the penis adequate for sexual intercourse. Also called impotence.
• erectionIn medicine, the swelling of the penis with blood, causing it to become firm.
• erenumabA human immunoglobulin G2 (IgG2) monoclonal antibody targeting calcitonin gene-related peptide receptor...
• erfonrilimabA bispecific monoclonal antibody directed against both the immunosuppressive ligand, programmed cell death-1...
• ergocalciferolA form of vitamin D that helps the body use calcium and phosphorus to make strong bones and teeth. It is...
• eribulin mesylateA drug used to treat certain types of breast cancer and liposarcoma (a type of soft tissue sarcoma) that have...
• erismodegibA drug used to treat locally advanced basal cell carcinoma (BCC) that has come back after surgery or...
• eritoranA synthetic analogue of the lipid A portion of the endotoxin lipopolysaccharide (LPS) with potential...
• eritoran tetrasodiumThe tetrasodium salt of a synthetic analogue of the lipid A portion of the endotoxin lipopolysaccharide (LPS)...
• ErivedgeA drug used to treat basal cell carcinoma that has spread to other parts of the body, has come back after...
• ERK 1/2 inhibitor ASTX029An orally bioavailable inhibitor of the extracellular signal-regulated kinases (ERK) 1 and 2, with potential...
• ERK inhibitor CC-90003An orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic...
• ERK inhibitor LTT462An orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic...
• ERK inhibitor MK-8353An orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic...
• ERK1/2 inhibitor ATG-017An orally bioavailable inhibitor of the extracellular signal-regulated kinases 1 (ERK1) and 2 (ERK2), with...
• ERK1/2 inhibitor ERAS-007An orally bioavailable inhibitor of the extracellular signal-regulated kinases 1 (ERK1) and 2 (ERK2), with...
• ERK1/2 inhibitor GH55An orally bioavailable and selective inhibitor of the extracellular signal-regulated kinases 1 (ERK1) and 2...
• ERK1/2 inhibitor HH2710An orally bioavailable inhibitor of the extracellular signal-regulated kinases 1 (ERK1) and 2 (ERK2), with...
• ERK1/2 inhibitor IPN01194An orally bioavailable inhibitor of the extracellular signal-regulated kinases 1 (ERK1) and 2 (ERK2), with...
• ERK1/2 inhibitor JSI-1187An orally bioavailable inhibitor of the extracellular signal-regulated kinases 1 (ERK1) and 2 (ERK2), with...
• ERK1/2 inhibitor KO-947An inhibitor of the extracellular signal-regulated kinases (ERK) 1 and 2, with potential antineoplastic...
• ERK1/2 inhibitor LY3214996An orally available inhibitor of extracellular signal-regulated kinase (ERK) 1 and 2, with potential...
• ErleadaA drug used to treat prostate cancer that has spread to other parts of the body and is castration sensitive...
• erlotinib hydrochlorideA drug used alone to treat certain types of non-small cell lung cancer and with gemcitabine hydrochloride to...
• ERMSA soft tissue tumor that is most common in infants and young children. It begins in muscles, usually in the...
• ER-negative PR-negative HER2/neu-negative breast cancerA type of breast cancer in which the tumor cells do not have estrogen receptors, progesterone receptors, or...
• ERTTreatment with the hormone estrogen to increase the amount of estrogen in the body. It is given to women who...
• ertapenem sodiumThe sodium salt of ertapenem, a 1-beta-methyl carbapenem and a broad-spectrum beta-lactam antibiotic with...
• ertumaxomabA murine monoclonal antibody with two antigen-recognition sites: one for CD3, an antigen expressed on mature...
• eructationThe release of air or gas from the stomach or esophagus through the mouth. Eructation is usually caused by a...
• ERUSA procedure in which a probe that sends out high-energy sound waves is inserted into the rectum. The sound...
• ErwinazeA drug that contains the active ingredient asparaginase Erwinia chrysanthemi and is used with other drugs to...
• eryaspaseA suspension of erythrocytes encapsulating L-asparaginase with potential antineoplastic activity. Upon...
• erythemaRedness of the skin.
• erythrocyteA type of blood cell that is made in the bone marrow and found in the blood. Erythrocytes contain a protein...
• erythrocyte sedimentation rateThe distance red blood cells travel in one hour in a sample of blood as they settle to the bottom of a test...
• erythrodysplasiaA condition in which immature red blood cells (erythroid cells) in the bone marrow are abnormal in size...
• erythrogenesis imperfectaA very rare disorder in which the bone marrow doesn’t make enough red blood cells. It is usually seen in the...
• erythroid dysplasiaA condition in which immature red blood cells (erythroid cells) in the bone marrow are abnormal in size...
• erythroleukemiaCancer of the blood-forming tissues in which large numbers of immature, abnormal red blood cells are found in...
• erythroleukoplakiaAn abnormal patch of red and white tissue that forms on mucous membranes in the mouth and may become cancer...
• erythromycinA broad-spectrum, topical macrolide antibiotic with antibacterial activity. Erythromycin diffuses through the...
• erythromycin topical creamA topical cream formulation containing the broad-spectrum macrolide antibiotic erythromycin with...
• erythroplakiaAn abnormal patch of red tissue that usually forms on the inside of the mouth, especially on the tongue...
• erythropoiesisThe formation of red blood cells in blood-forming tissue. In the early development of a fetus, erythropoiesis...
• erythropoiesis-stimulating agentA substance that stimulates the bone marrow to make more red blood cells. Erythropoiesis-stimulating agents...
• erythropoietinA substance that is naturally produced by the kidneys, and that stimulates the bone marrow to make red blood...
• erzotabartA hexamerization-enhanced human immunoglobulin G1 (IgG1) monoclonal antibody that targets the cell surface...
• ESAA substance that stimulates the bone marrow to make more red blood cells. ESAs are used to treat anemia...
• escitalopramA drug used to treat depression and certain anxiety disorders. It belongs to the family of drugs called...
• escitalopram oxalateThe oxalate salt of escitalopram, a pure S-enantiomer of the racemic bicyclic phthalane derivative...
• esketamineA cyclohexanone derivative and S-enantiomer of racemic ketamine, with analgesic, anesthetic and...
• esmololThe hydrochloride salt form of esmolol, a short, rapid-acting, selective beta-adrenergic receptor blocker...
• esomeprazole magnesiumA drug that blocks acid from being made in the stomach. It is used to treat acid reflux disease and to...
• esomeprazole topical creamA topical cream formulation containing the proton pump inhibitor (PPI) esomeprazole, with potential...
• esophagealHaving to do with the esophagus, the muscular tube through which food passes from the throat to the stomach.
• esophageal cancerCancer that forms in tissues lining the esophagus (the muscular tube through which food passes from the...
• esophageal refluxThe backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the...
• esophageal speechSpeech produced by trapping air in the esophagus and forcing it out again. It is used after removal of a...
• esophageal stentA tube placed in the esophagus to keep a blocked area open so the patient can swallow soft food and liquids...
• esophagectomyAn operation to remove a portion of the esophagus.
• esophagitisInflammation of the esophagus (the tube that carries food from the mouth to the stomach).
• esophagogastroduodenoscopyA procedure in which an endoscope is passed through the mouth and down the throat into esophagus, stomach...
• esophagoscopyExamination of the esophagus using an esophagoscope. An esophagoscope is a thin, tube-like instrument with a...
• esophagramA series of x-ray pictures of the esophagus taken after a patient drinks a liquid containing barium sulfate...
• esophagusThe muscular tube through which food passes from the throat to the stomach.
• esorubicinA synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin with potential...
• ESRThe distance red blood cells travel in one hour in a sample of blood as they settle to the bottom of a test...
• ESR1 geneA gene that makes one of the two main types of estrogen receptor (ER) proteins. These proteins bind to and...
• ESR1 peptides/GM-CSF/Montanide ISA vaccineA vaccine comprised of estrogen receptor alpha (ERa; estrogen receptor 1; ESR1) mutant peptides, combined...
• ESSA rare type of cancer that forms in the connective tissue of the lining of the uterus. It may also form in...
• essential oilThe scented liquid taken from certain plants using steam or pressure. Essential oils contain the natural...
• essential thrombocythemiaAn increased number of thrombocytes (platelets) in the blood, without a known cause. Also called essential...
• essential thrombocytosisAn increased number of thrombocytes (platelets) in the blood, without a known cause. Also called essential...
• EssiacAn herbal tea mixture that contains burdock root, Indian rhubarb root, sheep sorrel, and slippery elm bark...
• esterA chemical substance made when an acid and an alcohol combine and water is removed. Esters are found in...
• esterified estrogenA form of estrogen that may have fewer side effects than other forms. Esterified estrogens are used to treat...
• esthesioneuroblastomaA rare type of cancer that forms in the tissues of the upper part of the nasal cavity (space inside the...
• estradiolA form of the hormone estrogen.
• estradiol vaginal ringA flexible elastomer ring containing 17 beta-estradiol used for estrogen replacement. Upon vaginal insertion...
• estradiol valerateThe parenterally-administered synthetic valerate ester of estradiol, a steroid sex hormone vital to the...
• estradiol/norethindrone acetate tabletAn orally bioavailable tablet formulation containing the semisynthetic estrogen estradiol in combination with...
• estramustineA combination of the hormone estradiol (an estrogen) and nitrogen mustard (an anticancer drug). Used in the...
• estramustine phosphate sodiumThe orally available disodium salt, monohydrate, of estramustine phosphate, a synthetic molecule that...
• estriolA synthetic form of the endogenous human estriol, a weak oestrogen and natural metabolite of estradiol, that...
• estriol vaginal gelA vaginal gel formulation containing a very low concentration of the estrogen estriol, that can be used for...
• estrogenA type of hormone made by the body that helps develop and maintain female sex characteristics and the growth...
• estrogen blockerA substance that keeps cells from making or using estrogen (a hormone that plays a role in female sex...
• estrogen creamA cream that contains the hormone estrogen. It is used to treat some symptoms of menopause, such as vaginal...
• estrogen receptorA protein found inside the cells of the female reproductive tissue, some other types of tissue, and some...
• estrogen receptor agonist GTx-758An orally available, nonsteroidal selective estrogen receptor (ER) alpha agonist with potential...
• estrogen receptor degrader AC699An orally bioavailable estrogen receptor (ER)-targeted chimeric protein degrader composed of ligands of ER...
• estrogen receptor negativeDescribes cells that do not have a protein that binds to the hormone estrogen. Cancer cells that are estrogen...
• estrogen receptor positiveDescribes cells that have a protein that binds to the hormone estrogen. Cancer cells that are estrogen...
• estrogen receptor testA lab test to find out if cancer cells have estrogen receptors (proteins to which estrogen will bind). If the...
• estrogen replacement therapyTreatment with the hormone estrogen to increase the amount of estrogen in the body. It is given to women who...
• esuberaprost sodiumThe sodium salt form of esuberaprost, the 314-d isomer of beraprost, with potential anti-inflammatory...
• eszopicloneA nonbenzodiazepine cyclopyrrolone and active dextrorotatory stereoisomer of zopiclone with hypnotic and...
• ET 743A drug used to treat liposarcoma and leiomyosarcoma (types of soft tissue sarcoma) that cannot be removed by...
• etalocibA second-generation selective leukotriene B4 receptor (LTB4R) antagonist with potential antineoplastic...
• etanerceptA drug that is commonly used to treat arthritis. It is also being studied in the treatment of cancer, and as...
• etanidazoleA 2-nitroimidazole with radiosensitizing properties. Etanidazole depletes glutathione and inhibits...
• etaracizumabA substance being studied in the treatment of some types of cancer and other conditions. Etaracizumab binds...
• etavopivatAn orally available, small-molecule allosteric activator of the selective red blood cell (RBC) isoform of...
• etelcalcetideA calcimimetic and calcium-sensing receptor (CaSR) agonist composed of a synthetic peptide comprised of seven...
• ethacrynic acidAn aryloxy-acetic acid derivative belonging to the class of loop diuretics. Ethacrynic acid interferes with...
• ethambutolAn antibiotic with bacteriostatic, antimicrobial and antitubercular properties. Ethambutol interferes with...
• ethanol ablationAn injection of ethanol (alcohol) through the skin directly into a tumor to kill cancer cells. Ultrasound or...
• ethanol-containing nasal solutionAn intranasal solution containing ethanol with antimicrobial activity. Upon intranasal application...
• ethaselenAn orally bioavailable organoselenium inhibitor of thioredoxin reductase 1 (TrxR1), with potential...
• etheylenediaminetetraacetic acidA chemical that binds certain metal ions, such as calcium, magnesium, lead, and iron. It is used in medicine...
• ethicalHaving to do with beliefs about what is right and wrong in terms of how people behave. Also called moral.
• ethical willA final personal message or document in which a person shares his or her thoughts, values, memories, life...
• ethinyl estradiolA semisynthetic estrogen. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus...
• ethinyl estradiol/levonorgestrelA combination of two steroid sex hormones, an estrogen and a progestin, used for contraceptive purposes...
• ethinyl estradiol/norethindroneAn oral contraceptive formulation containing the semisynthetic estrogen, ethinyl estradiol, combined with the...
• ethiodized oilA form of poppy seed oil that contains iodine. Ethiodized oil is given by injection and builds up in the...
• EthiodolA form of poppy seed oil that contains iodine. Ethiodol is given by injection and builds up in the blood and...
• ethmoid sinusA type of paranasal sinus (a hollow space in the bones around the nose). Ethmoid sinuses are found in the...
• ethnic groupA group of people who share a similar culture (beliefs, values, and behaviors), language, religion, ancestry...
• ethnicityA term that refers to the social and cultural characteristics, backgrounds, or experiences shared by a group...
• ethosuximideA succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but...
• ethyl alcohol mouthwashA mouthwash containing ethyl alcohol, with topical antibacterial activity. Upon rinsing the oral cavity with...
• ethyl icosapentateA highly purified omega-3 fatty acid that can decrease serum triglyceride levels. Ethyl icosapentate reduces...
• ethylene oxideA chemical used to make antifreeze, to clean medical equipment, and as a pesticide. It is also found in...
• ethylene-vinyl alcohol copolymer-based embolic agentA non-adhesive, non-absorbable, permanent liquid embolic agent comprised of ethylene vinyl alcohol (EVOH)...
• ethynyluracilAn anticancer drug that increases the effectiveness of fluorouracil. Also called eniluracil.
• EthyolA drug used to help protect the kidneys in patients receiving cisplatin for advanced ovarian cancer and to...
• etidronateA drug that belongs to the family of drugs called bisphosphonates. Bisphosphonates are used as treatment for...
• Etidronate-Cytarabine Conjugate MBC-11A synthetic conjugate composed of the bisphosphonate etidronate linked to the cytostatic agent and...
• etigilimabA monoclonal antibody targeting the human co-inhibitory molecule and immune checkpoint inhibitor T-cell...
• etiologyThe cause or origin of disease.
• etirinotecan pegolAn extended-release (ER) formulation composed of irinotecan, which is a semisynthetic derivative of...
• etodolacA pyranocarboxylic acid and non-steroidal anti-inflammatory drug (NSAID) with antipyretic and analgesic...
• EtopophosA drug used with other drugs to treat small cell lung cancer and certain types of testicular cancer. It is...
• etoposideThe active ingredient in a drug used with other drugs to treat small cell lung cancer and certain types of...
• etoposide phosphateA drug used with other drugs to treat small cell lung cancer and certain types of testicular cancer. It is...
• etoposide toniribateA prodrug of etoposide, a semisynthetic derivative of podophyllotoxin extracted from the mandrake root...
• etoricoxibA synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic ,and potential...
• etrumadenantAn orally bioavailable antagonist of both the immunomodulatory checkpoint molecules adenosine A2A receptor...
• ETSSmoke that comes from the burning of a tobacco product and smoke that is exhaled by smokers. Inhaling ETS is...
• Ets-family transcription factor inhibitor TK216A proprietary biologic that inhibits the transcriptional-promoting activity of E26 transformation-specific...
• eucalyptusA type of evergreen tree that is a member of the myrtle family. Oil from the leaves is used in very small...
• euphoriaA feeling of great happiness or well-being. Euphoria may be a side effect of certain drugs.
• eurestobartA humanized immunoglobulin G1 (IgG1) monoclonal antibody directed against the cell surface receptor CD39...
• EUSA procedure in which an endoscope is inserted into the body. An endoscope is a thin, tube-like instrument...
• EUS-FNAA procedure to take a sample of tissue for examination under a microscope. An endoscope with an ultrasound...
• euthanasiaAn easy or painless death, or the intentional ending of the life of a person suffering from an incurable or...
• evaluable diseaseDisease that cannot be measured directly by the size of the tumor but can be evaluated by other methods...
• evaluable patientsPatients whose response to a treatment can be measured because enough information has been collected.
• Evaux spring water-based creamA cream containing Evaux thermal spring water, with potential moisturizing and skin protecting activities...
• Evaux spring water-based topical sprayA skin spray composed of Evaux thermal spring water, the emulsifier polysorbate 20, the preservatives...
• Evaux thermal spring water-based solutionA topical solution containing Evaux thermal spring water, with potential moisturizing and skin protecting...
• event-free survivalIn cancer, the length of time after primary treatment for a cancer ends that the patient remains free of...
• everolimusA drug used alone or with other drugs to treat certain types of breast cancer, kidney cancer, and pancreatic...
• everolimus tablets for oral suspensionTablets for oral suspension containing everolimus, a derivative of the natural macrocyclic lactone sirolimus...
• everolimus/exemestane regimenA regimen consisting of everolimus and exemestane that is used as a treatment for breast cancer.
• evexomostatA synthetic copolymer-drug conjugate of a fumagillin-derived methionine aminopeptidase 2 (MetAP2) inhibitor...
• evidence-based medicineA systematic approach to medicine in which doctors and other health care professionals use the best available...
• EvistaA drug used to reduce the risk of invasive breast cancer in postmenopausal women who are at high risk of...
• eVLP CMV gB-pp65 plus GM-CSF VBI-1901A cancer vaccine composed of enveloped virus-like particles (eVLPs) containing the human cytomegalovirus...
• evocalcetAn orally available calcium receptor (CaR) modulator, with potential calcimimetic activity. Upon...
• evofosfamideA hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard (Br-IPM) conjugated with...
• EvomelaA drug that contains the active ingredient melphalan hydrochloride and is given as an infusion to prepare...
• EvorpaceptA variant of signal regulatory protein alpha (SIRPa) that antagonizes the human cell surface antigen CD47...
• EvoxacA drug used to treat certain disorders of the salivary gland. It is also being studied as a treatment for dry...
• Ewing sarcomaA type of cancer that forms in bone or soft tissue. Also called peripheral primitive neuroectodermal tumor...
• Ewing sarcoma family of tumorsA group of cancers that includes Ewing tumor of bone (ETB or Ewing sarcoma of bone), extraosseous Ewing (EOE)...
• ex vivoOutside of the living body. Refers to a medical procedure in which an organ, cells, or tissue are taken from...
• ex vivo-activated autologous lymph node lymphocytesAutologous human lymph node T-lymphocytes, with potential immunostimulatory and antineoplastic activity. Upon...
• ex vivo-expanded allogeneic gamma 9 delta 2 T cellsA preparation of a subset of ex vivo-expanded, allogeneic T lymphocytes that express gamma 9 delta 2 T-cell...
• ex vivo-expanded autologous T cells IMA101A preparation of autologous cytotoxic T lymphocytes, specifically recognizing certain tumor-associated...
• ex vivo-expanded HER2-specific T cellsT cells specific for the human epidermal growth factor receptor 2 (HER2) with potential immunopotentiating...
• ExalgoA drug used to treat moderate to severe pain. It may also be used to treat certain types of cough. Exalgo is...
• exatecan mesylateAn anticancer drug that is a type of topoisomerase inhibitor. Also called DX-8951f.
• excisional biopsyA surgical procedure in which a cut is made through the skin to remove an entire lump or suspicious area so...
• excisional skin surgeryA surgical procedure used to remove moles, cysts, skin cancer, and other skin growths using local anesthesia...
• excreteTo get rid of waste material from the blood, tissues, or organs by a normal discharge (such as sweat, urine...
• exemestaneA drug used to treat postmenopausal women with advanced breast cancer or early-stage breast cancer that is...
• exenatideA 39 amino acid peptide and synthetic version of exendin-4, a hormone found in the saliva of the venomous...
• exenterationSurgery to remove organs within a body cavity.
• exicorilantAn orally available, selective glucocorticoid receptor (GR) antagonist, with potential antineoplastic...
• existential therapyA type of psychotherapy that helps people think about the problems in their lives in the context of larger...
• exisulindA drug being studied in the treatment and prevention of cancer. It has been shown to cause apoptosis (cell...
• ExjadeA drug used to treat too much iron in the blood caused by blood transfusions. It is being studied in the...
• exlinkibartA humanized agonistic monoclonal antibody targeting the costimulatory receptor CD137 (4-1BB; tumor necrosis...
• exocervixThe outer part of the cervix that opens into the vagina. The exocervix is lined with squamous cells (thin...
• exocrine glandA gland that makes substances such as sweat, tears, saliva, milk, and digestive juices, and releases them...
• exocrine pancreas cellA pancreatic cell that produces enzymes that are secreted into the small intestine. These enzymes help digest...
• exonThe sequence of DNA that is present in the final, mature messenger RNA transcript. Most exons code for amino...
• exosomeA tiny sac-like structure that is formed inside a cell and contains some of the cell’s proteins, DNA, and...
• expanded accessA way to provide an investigational therapy to a patient who is not eligible to receive that therapy in a...
• expanded cord blood stem cells mixed with engineered human endothelial cells AB-110A population of ex vivo expanded, CD34-positive-enriched hematopoietic progenitor cells (HPCs), which are...
• expanded/activated gamma/delta T lymphocytesA preparation of gamma delta T lymphocytes derived from donor T cells that have been expanded and activated...
• expectant managementClosely watching a patient’s condition but not giving treatment unless symptoms appear or change, or there...
• experimentalIn clinical trials, refers to a drug (including a new drug, dose, combination, or route of administration) or...
• experimental drugA substance that has been tested in the laboratory and has been approved by the U.S. Food and Drug...
• experimental groupThe group in a clinical research study that receives the drug, vaccine, or other intervention being tested...
• explanation of benefitsA summary of the costs of a medical treatment or other health care service that an insurance company may send...
• exploratory surgerySurgery to look inside the body to help make a diagnosis.
• extended release bupivacaine hydrochloride resorbable matrix formulationAn extended release (ER) injectable formulation composed of the hydrochloride salt form of bupivacaine, an...
• extended release metformin hydrochlorideAn extended-release (ER) tablet composed of the hydrochloride salt form of the biguanide metformin, with...
• extended-release flucytosineAn extended release (ER) oral tablet that contains flucytosine (5-FC), a fluorinated cytosine analog, with...
• extended-release galantamine hydrobromideAn extended-release (ER) formulation of the hydrobromide salt form of galantamine, a tertiary alkaloid...
• extended-release granisetron polymer formulationAn extended-release (ER), polymer-based injectable formulation containing the indazole derivative...
• extended-release MetAP2 inhibitor APL-1501An extended-release (ER) formulation of APL-1501, an orally available inhibitor of methionine aminopeptidase...
• extended-release microsphere capsule-based oxycodoneA wax microsphere capsule formulation of oxycodone, a semi-synthetic, morphine-like opioid alkaloid, with...
• extended-release onapristoneAn extended-release (ER) formulation of onapristone, an orally bioavailable progesterone receptor (PR)...
• extensive-stage small cell lung cancerCancer has spread outside of the lung in which it began or to other parts of the body.
• external beam radiation therapyA type of radiation therapy that uses a machine outside the body to send high-energy radiation beams toward...
• external radiation therapyA type of radiation therapy that uses a machine outside the body to send high-energy radiation beams toward...
• external right atrial catheterA thin, flexible tube that is inserted into a vein in the neck or below the collar bone and guided (threaded)...
• extracellular matrixA large network of proteins and other molecules that surround, support, and give structure to cells and...
• extracorporeal photopheresisA procedure in which blood is removed from the body and treated with ultraviolet light and drugs that become...
• extracranialOutside of the cranium (bones that surround the brain).
• extracranial germ cell tumorA type of tumor that begins in germ cells (cells that form sperm or eggs) that are found in areas of the body...
• extractIn medicine, a preparation of a substance obtained from plants, animals, or bacteria and used as a drug or in...
• extragonadalAn area of the body other than the ovaries or testes.
• extragonadal extracranial germ cell tumorA rare type of tumor that begins in germ cells (cells that form sperm or eggs) found in areas of the body...
• extragonadal germ cell tumorA rare cancer that develops in germ cells that are found in areas of the body other than the ovary or...
• extrahepaticLocated or occurring outside the liver.
• extrahepatic bile ductA duct (tube) that is outside the liver and carries bile from the liver and gallbladder to the small...
• extrahepatic bile duct cancerA rare cancer that forms in the bile ducts (tubes) outside the liver. Bile ducts carry bile from the liver...
• extramedullary myeloid tumorA rare type of cancer that is made up of myeloblasts (a type of immature white blood cell) and forms outside...
• extranodalRefers to an area or organ outside of the lymph nodes.
• extraocularLocated outside the eye.
• extraosseousLocated or occurring outside of the bone. Also called extraskeletal.
• extraosseous Ewing tumorA rare type of Ewing sarcoma that forms in soft tissue instead of bone. It usually occurs in the chest...
• extraosseous osteosarcomaA rare, fast-growing type of cancer that is made up of bone and cartilage cells, and forms in soft tissue...
• extrapleural pneumonectomySurgery to remove a diseased lung, part of the pericardium (membrane covering the heart), part of the...
• extrarenal (extracranial) rhabdoid tumorA rare, fast-growing cancer that forms in the soft tissues of the liver, heart, peritoneum, or other areas of...
• extraskeletalLocated or occurring outside of the bone. Also called extraosseous.
• extraskeletal Ewing sarcomaA rare type of Ewing sarcoma that forms in soft tissue instead of bone. It usually occurs in the chest...
• extraskeletal Ewing tumorA rare type of Ewing sarcoma that forms in soft tissue instead of bone. It usually occurs in the chest...
• extraskeletal mesenchymal chondrosarcomaA rare type of cancer that forms in cartilage or other soft tissue but not in bone. It usually occurs in the...
• extraskeletal myxoid chondrosarcomaA rare, slow-growing type of cancer that forms in soft tissues outside the bone and usually has certain...
• extraskeletal osteosarcomaA rare, fast-growing type of cancer that is made up of bone and cartilage cells, and forms in soft tissue...
• extrauterine pregnancyA condition in which a fertilized egg grows outside of the uterus, usually in one of the fallopian tubes...
• extravasationThe leakage of blood, lymph, or other fluid, such as an anticancer drug, from a blood vessel or tube into the...
• extravasation injuryBlistering and tissue damage caused by certain drugs when they leak out of a vein into the tissue around it...
• extremely dense breast tissueA term used to describe breast tissue that is made up of almost all dense fibrous tissue and glandular...
• extremely low frequency electromagnetic fieldA type of very low-energy radiation that travels in long waves. Although there have been health concerns, it...
• extremityA limb of the body, such as the arm or leg.
• eye cancerCancer that forms in tissues of and around the eye. Some of the cancers that may affect the eye include...
• eye socketThe space within the skull that contains the eye, including its nerves and muscles. The eye socket also...
• ezabenlimabA monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed...
• ezatiostat hydrochlorideThe hydrochloride salt of a liposomal small-molecule glutathione analog inhibitor of glutathione...
• ezetimibeAn azetidinone derivative and a cholesterol absorption inhibitor with lipid-lowering activity. Ezetimibe...
• ezetimibe/simvastatinAn orally bioavailable combination agent containing the cholesterol absorption inhibitor ezetimibe and the...
• EZH1/2 inhibitor HH2853An orally bioavailable inhibitor of the histone lysine methyltransferases enhancer of zeste homolog 1 (EZH1)...
• EZH2 geneA gene that makes a protein that is involved in controlling the activity of certain genes and in cell...
• EZH2 inhibitor CPI-1205An orally available selective inhibitor of the histone lysine methyltransferase EZH2, with potential...
• EZH2 inhibitor PF-06821497An orally available selective inhibitor of the histone lysine methyltransferase (HMT) enhancer of zeste...
• EZH2 inhibitor SHR2554An orally available selective inhibitor of the histone lysine methyltransferase (HMT) enhancer of zeste...
• EZN-2285A drug used with other drugs to treat acute lymphoblastic leukemia in children and young adults aged 1 month...
• ezurpimtrostatAn orally bioavailable, quinolone-derived, small molecule inhibitor of palmitoyl-protein thioesterase 1...

774 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.