Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: I (791)

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• intoxicating pepperAn herb native to islands in the South Pacific. Substances taken from the root have been used in some...
• intra-arterialWithin an artery (blood vessel that carries blood from the heart to tissues and organs in the body).
• intra-arterial brachytherapyA type of radiation therapy used to treat liver cancer or cancer that has spread to the liver. A thin...
• intracarotid infusionThe introduction of fluids and drugs directly into the carotid artery, the main artery in the neck that...
• intracavitaryWithin a cavity or space, such as the abdomen, pelvis, or chest.
• intracavitary radiation therapyA type of internal radiation therapy in which radioactive material sealed in needles, seeds, wires, or...
• intracellularInside a cell.
• intracellular matrixThe large network consisting of protein fibers and other molecules that gives shape and structure to cells in...
• intracolonicWithin the colon.
• intracranial tumorA tumor that occurs in the brain.
• intracutaneousWithin the skin. Also called intradermal.
• intradermalWithin the skin. Also called intracutaneous.
• intraductal breast carcinomaA condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not...
• intraductal breast papillomaA benign (not cancer), wart-like growth in a milk duct of the breast. It is usually found close to the nipple...
• intraductal carcinoma of the prostateA type of cancer that usually begins in the glandular (secretory) tissue that lines the prostate and spreads...
• intraductal papillomaA benign (not cancer), wart-like growth in a milk duct of the breast. It is usually found close to the nipple...
• intraductal prostate carcinomaA type of cancer that usually begins in the glandular (secretory) tissue that lines the prostate and spreads...
• intraepithelialWithin the layer of cells that form the surface or lining of an organ.
• intraepithelial neoplasiaA term used to describe the presence of abnormal cells on the surface of or in the tissue that lines an...
• intrahepaticWithin the liver.
• intrahepatic bile ductA bile duct that passes through and drains bile from the liver.
• intrahepatic bile duct cancerA rare cancer that forms in the bile ducts inside the liver. A bile duct is a tube that carries bile (fluid...
• intrahepatic infusionThe delivery of anticancer drugs directly to the blood vessels of the liver.
• intralesionalWithin an area of cancer, for example, within a tumor in the skin.
• intraluminal intubation and dilationA procedure in which a plastic or metal tube is inserted through the mouth into the esophagus (the tube that...
• intramuscularWithin or into muscle. Also called IM.
• intramuscular injectionInjection into muscle.
• intranasal ketamineAn intranasal formualtion of the synthetic cyclohexanone ketamine with analgesic and anesthetic activities...
• in-transit metastasisA type of metastasis in which skin cancer spreads through a lymph vessel and begins to grow more than 2...
• intraocularWithin the eyeball.
• intraocular melanomaA rare cancer that begins in the cells that make the dark-colored pigment, called melanin, in the uvea or...
• intraoperative radiation therapyRadiation treatment aimed directly at a tumor during surgery. Also called IORT.
• intraoperative ultrasoundA procedure that uses ultrasound (high-energy sound waves that are bounced off internal tissues and organs)...
• intrapelvicWithin the pelvis, the lower part of the abdomen between the hip bones.
• intrapericardial chemotherapyA type of treatment in which anticancer drugs are injected through a thin tube directly into the pericardium...
• intraperitonealWithin the peritoneal cavity (the area that contains the abdominal organs). Also called IP.
• intraperitoneal chemotherapyTreatment in which anticancer drugs are put directly into the abdominal cavity through a thin tube.
• intraperitoneal infusionA method of delivering fluids and drugs directly into the abdominal cavity through a thin tube. Also called...
• intraperitoneal radiation therapyTreatment in which a radioactive liquid is put directly into the abdomen through a thin tube.
• intrapleuralWithin the pleural cavity.
• intraspinalWithin the spine (backbone).
• intrathecalDescribes the fluid-filled space between the thin layers of tissue that cover the brain and spinal cord...
• intrathecal chemotherapyTreatment in which anticancer drugs are injected into the fluid-filled space between the thin layers of...
• intrathecal deferoxamineAn intrathecal (IT) formulation of deferoxamine (DFO), an iron-chelating agent that can be used to deplete...
• intratumoralWithin a tumor.
• intrauterineInside the uterus (the small, hollow, pear-shaped organ in a woman’s pelvis in which a fetus develops).
• intrauterine deviceA small, plastic T-shaped device that is placed inside the uterus (the small, hollow, pear-shaped organ in a...
• intravaginalHaving to do with the inside of the vagina (the birth canal).
• intravasationThe movement of a cell or a foreign substance through the wall of a blood or lymph vessel into the vessel...
• intravenousInto or within a vein. Intravenous usually refers to a way of giving a drug or other substance through a...
• intravenous chemotherapyTreatment in which anticancer drugs are given through a needle or tube inserted into a vein. The anticancer...
• intravenous immunoglobulinA substance made from antibodies that have been taken from the blood of many healthy donors. It is given to a...
• intravenous infusionA method of putting fluids, including drugs, into the bloodstream. Also called infusion.
• intravenous injectionInjection into a vein.
• intravenous pyelogramAn x-ray image of the kidneys, ureters, and bladder, and prostate in men, that is taken after a contrast dye...
• intravenous pyelographyAn x-ray exam of the kidneys, ureters, and bladder, and prostate in men, that uses a contrast dye injected...
• intravenous urogramAn x-ray image of the kidneys, ureters, and bladder, and prostate in men, that is taken after a contrast dye...
• intravenous urographyAn x-ray exam of the kidneys, ureters, and bladder, and prostate in men, that uses a contrast dye injected...
• intraventricular infusionThe delivery of a drug into a fluid-filled cavity within the heart or brain.
• intravesicalWithin the bladder.
• intravesical chemotherapyTreatment in which anticancer drugs are put directly into the bladder through a thin, flexible tube inserted...
• intravitreal chemotherapyTreatment in which anticancer drugs are injected directly into the vitreous humor (gel-like fluid inside the...
• intronThe sequence of DNA in between exons that is initially copied into RNA, but is cut out of the final, mature...
• Intron AA drug used alone or with other drugs to treat adults with AIDS-related Kaposi sarcoma, hairy cell leukemia...
• intrusive thoughtAn unpleasant memory or idea that occurs often in a person’s everyday thoughts and keeps him or her from...
• intubationA procedure in which a tube is inserted through the mouth or nose into the trachea (windpipe) or into a...
• inulinA naturally occurring, indigestible and non-absorbable oligosaccharide produced by certain plants with...
• inupadenantAn orally bioavailable immune checkpoint inhibitor and antagonist of the adenosine A2A receptor (A2AR...
• invariant natural killer T cellsA natural killer T-cell subtype bearing an invariant T-cell receptor. Invariant natural killer T cells...
• invasive breast cancerCancer that has spread from where it began in the breast to surrounding normal tissue. The most common type...
• invasive cancerCancer that has spread beyond the layer of tissue in which it developed and is growing into surrounding...
• invasive cervical cancerCancer that has spread from the surface of the cervix to tissue deeper in the cervix or to other parts of the...
• invasive ductal carcinomaThe most common type of invasive breast cancer. It begins in the lining of the milk ducts (thin tubes that...
• invasive hydatidiform moleA type of cancer that grows into the muscular wall of the uterus. It is formed after conception...
• invasive lobular carcinomaA type of invasive breast cancer that begins in the lobules (milk glands) of the breast and spreads to...
• invasive procedureA medical procedure that invades (enters) the body, usually by cutting or puncturing the skin or by inserting...
• inversionA chromosomal defect in which a segment of the chromosome breaks off and reattaches in the reverse direction.
• inverted nippleA nipple that turns inward into the breast or lies flat against the breast. An inverted nipple may be present...
• inverted papillomaA type of tumor in which surface epithelial cells grow downward into the underlying supportive tissue. It may...
• investigationalIn clinical trials, refers to a drug (including a new drug, dose, combination, or route of administration) or...
• investigational agentA substance that has been tested in the laboratory and has been approved by the U.S. Food and Drug...
• investigational drugA substance that has been tested in the laboratory and has been approved by the U.S. Food and Drug...
• investigational groupThe group in a clinical research study that receives the drug, vaccine, or other intervention being tested...
• investigational new drugA substance that has been tested in the laboratory and has been approved by the U.S. Food and Drug...
• investigatorIn research, a person who is involved in running a clinical trial or research study. The investigator may...
• inviableNot able to survive.
• involuntaryAn action that is not made by choice. In the body, involuntary actions (such as blushing) occur...
• involuntary nervous systemThe part of the nervous system that controls muscles of internal organs (such as the heart, blood vessels...
• iobenguaneA synthetic, aralkylguanidine analogue of the adrenergic neurotransmitter norepinephrine (NE) and adrenergic...
• iobenguane I 123A drug containing a form of radioactive iodine called I 123 that is used to find certain types of tumors...
• iobenguane I 131A drug that contains a form of radioactive iodine and is used to treat adults and children aged 12 years and...
• iobenguane scanA procedure used to find neuroendocrine tumors, such as neuroblastomas and pheochromocytomas. A small amount...
• iobitridolA water-soluble, tri-iodinated, non-ionic monomeric benzoate derivative and contrast medium used in...
• iodinated contrast agentA contrast agent containing an iodine-based dye used in many diagnostic imaging examinations, including...
• iodinated polyethylene glycol-based hydrogel tissue markerA radiopaque hydrogel containing cross-linked, iodinated polyethylene glycol (PEG) particles in a viscous...
• iodineAn element that is necessary for the body to make thyroid hormone. It is found in shellfish and iodized salt.
• iodine 131-6-beta-iodomethyl-19-norcholesterolA radioiodine-labeled cholesterol analogue with radioisotopic activity. Iodine...
• iodine I 123A radioactive isotope of iodine, a nonmetallic element of the halogen group with an atomic mass of 123 and a...
• iodine I 123 ADAMA radiopharmaceutical containing the serotonin transporter (SERT) ligand ADAM...
• iodine I 123 anti-CEA recombinant diabody T84.66A radioimmunoconjugate comprised of a recombinant scFv dimer diabody of a monoclonal antibody against human...
• iodine I 123 iodometomidateAn iodine I-123 conjugate of metomidate (MTO) with potential application in adrenal imaging. Metomidate is a...
• iodine I 123-metaiodobenzylguanidineA drug containing a form of radioactive iodine called I 123 that is used to find certain types of tumors...
• iodine I 124A radioactive isotope of iodine, a nonmetallic element of the halogen group, with an atomic mass of 124 and a...
• iodine I 124 18B10(10L)A radioconjugate composed of an antibody directed against the tumor-associated antigen (TAA) Claudin18.2...
• iodine I 124 CPD-1028A radioconjugate composed of the insulin-like growth factor 1 receptor (IGF-1R) binding agent CPD-1028 and...
• iodine I 124 FIAUA radioconjugate containing the nucleoside analog 2'-fluoro-2'-deoxy-1beta-D-arabinofuranosyl-5-iodouracil...
• iodine I 124 hJAA-F11A radioimmunoconjugate composed of a humanized form of the mouse monoclonal antibody JAA-F11 (hJAA-F11)...
• iodine I 124 iobenguaneA radioconjugate composed of the positron-emitting radioisotope iodine I 124 labeled to iobenguane, the...
• iodine I 124 iodo-azomycin galactopyranosideA diagnostic radiopharmaceutical comprised of iodo-azomycin galactopyranoside (IAZGP) labeled with the...
• iodine I 124 iododeoxyuridineA radiopharmaceutical comprised of the thymidine analog, 5-iodo-2-deoxyuridine (idoxuridine), labeled with...
• iodine I 124 monoclonal antibody 3F8A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with...
• iodine I 124 monoclonal antibody A33A radioimmunoconjugate of a humanized monoclonal antibody (MoAb) A33 labelled with iodine 124 (I-124). MoAb...
• iodine I 124 monoclonal antibody M5AA radioimmunoconjugate comprised of M5A, a humanized monoclonal antibody directed against carcinoembryonic...
• iodine I 124 NM404A phospholipid ether analog labeled with iodine I 124, with a potential imaging property upon positron...
• iodine I 124 omburtamabA radioimmunoconjugate consisting of the iodine I 124-radiolabeled murine IgG1 monoclonal antibody omburtamab...
• iodine I 124 phospholipid ether analogue CLR1404A small molecule radiopharmaceutical composed of the radioisotope iodine I 124 covalently attached to a...
• iodine I 124 PU-ADA radioconjugate composed of PU-AD, a synthetic purine-scaffold inhibitor of the molecular chaperone heat...
• iodine I 124-cRGDY-PEG-C dotsAn imaging agent composed of silica-based nanoparticles labeled with a near-infrared (NIR) fluorophore...
• iodine I 124-labeled anti-phosphatidylserine monoclonal antibody PGN650A radioimmunoconjugate composed of the F(ab')2 fragment of human monoclonal antibody PGN650 against...
• iodine I 124-labeled anti-PSCA A11 minibodyA radioconjugate composed of an affinity-matured antibody fragment, the A11 minibody, directed against human...
• iodine I 124-labeled HSP90 inhibitor PUH71A radioconjugate containing the purine scaffold heat shock protein 90 (Hsp90) inhibitor PUH71 labeled with...
• iodine I 125A radioactive isotope of iodine, a nonmetallic element of the halogen group. With a half-life of 60 days...
• iodine I 125 anti-EGFR-425 monoclonal antibodyA radioimmunoconjugate consisting of a murine IgG2a monoclonal antibody directed against the human epidermal...
• iodine I 131 anti-fibronectin antibody fragment L19-SIPAn iodine 131 radioimmunoconjugate of a small immunoprotein (SIP), derived from the variable region fragment...
• iodine I 131 apamistamabA radioimmunoconjugate consisting of BC8, a murine IgG1 anti-CD45 monoclonal antibody labeled with iodine 131...
• iodine I 131 chimeric monoclonal antibody G-250A radioimmunoconjugate comprised of the chimeric monoclonal antibody G-250 conjugated with iodine I 131 with...
• iodine I 131 iodocholesterolA radioiodine-labeled cholesterol analogue with diagnostic imaging activity upon scintigraphy. Upon...
• iodine I 131 iopofosineA radioconjugate composed of iopofosine, a phospholipid ether analog, labeled with the radioactive isotope...
• iodine I 131 IPAA radioconjugate consisting of the tumor-specific amino acid derivative 4-iodo-L-phenylalanine labeled with...
• iodine I 131 MIP-1095A radioconjugate composed of MIP-1095, a urea-based ligand for the tumor-associated antigen (TAA)...
• iodine I 131 monoclonal antibody 3F8A radioimmunoconjugate consisting of 3F8, a murine anti-GD2 ganglioside monoclonal antibody labeled with...
• iodine I 131 monoclonal antibody 81C6A radioimmunoconjugate consisting of 81C6, a murine IgG2 anti-tenascin monoclonal antibody labeled with...
• iodine I 131 monoclonal antibody CC49-deltaCH2A radioimmunoconjugate consisting of the humanized CH2 domain-deleted monoclonal antibody CC49 and iodine I...
• iodine I 131 monoclonal antibody F16SIPA fully human monoclonal antibody (MoAb) against human A1 domain of tenascin-C, in small immunoprotein (SIP)...
• iodine I 131 monoclonal antibody muJ591A radioimmunoconjugate of a mouse monoclonal antibody (MoAb) J591 labeled with Iodine 131 (I-131). MoAb...
• iodine I 131 monoclonal antibody TNT-1/BAn iodine 131 labeled radioimmunoconjugate of monoclonal antibody (MOAB) TNT-1/B with radioimaging and...
• iodine I 131 NM404A phospholipid ether analog labeled with iodine I 131, with potential radiotherapeutic and radioimaging...
• iodine I 131 omburtamabA radioimmunoconjugate consisting of the iodine 131-radiolabeled murine IgG1 monoclonal antibody 8H9 directed...
• iodine I 131 rituximabA radioimmunoconjugate comprised of rituximab, a recombinant chimeric monoclonal antibody directed against...
• iodine I 131 SGMIB-anti-HER2 VHH1A monoclonal antibody (MoAb) directed against the human epidermal growth factor receptor 2 (HER2; ERBB2)...
• iodine I 131 tenatumomabA radioimmunoconjugate of tenatumomab, a murine monoclonal antibody targeting the tumor-associated antigen...
• iodine I 131 TM-601An iodine 131 (I 131) radioconjugate of the synthetic chlorotoxin (CTX) TM-601 with potential antiangiogenic...
• iodine I 131-ethiodized oilA radioactive substance being studied in the treatment of liver cancer. It is a form of poppy seed oil that...
• iodine I 131-labeled anti-CEA/anti-HSG bispecific monoclonal antibody TF2A tri-Fab bispecific monoclonal antibody (BiMoAb) divalent for the carcinoembryonic antigen (CEA) and...
• iodine I 131-LipiodolA radioactive substance being studied in the treatment of liver cancer. It is a form of poppy seed oil that...
• iodine I 131-metaiodobenzylguanidineA drug that contains a form of radioactive iodine and is used to treat adults and children aged 12 years and...
• iodine I 131-monoclonal antibody BC8A substance being studied in the treatment of some types of leukemia and lymphoma. BC8 is a monoclonal...
• iodine I 131-tositumomabA drug used with another drug to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied...
• iodine I-124 girentuximabA radioimmunoconjugate comprised of the chimeric monoclonal antibody G250 conjugated with the positron...
• iodine I-131A radioactive isotope of iodine with an atomic mass of 131, a half life of eight days, and potential...
• iodine-123 metaiodobenzylguanidineThe neurotransmitter analogue 3-nitrobenzylguanidine conjugated to iodine I 123 and used as a gamma-emitting...
• iodixanolA dimeric iso-osmolar, non-ionic, hydrophilic iodinated radiocontrast agent used in diagnostic imaging. Upon...
• iodized oilA form of poppy seed oil that contains iodine. Iodized oil is given by injection and builds up in the blood...
• iododoxorubicinA substance that is being studied as a treatment for cancer and for primary systemic amyloidosis (a disease...
• ioflubenzamide I-131An iodine 131-radiolabeled small-molecule benzamide compound with potential antineoplastic activity. The...
• iofolastat I123An iodine 123-radiolabled small molecule that exhibits high affinity for prostate-specific membrane antigen...
• iohexolAn X-ray contrast medium containing iohexol in various concentrations, from 140 to 350 milligrams of iodine...
• iolopride I-123A radiopharmaceutical containing the dopamine D2/D3 receptor agonist iodobenzamide (IBZM) labeled with the...
• ionAn atom or a molecule that has a positive or negative electrical charge. Examples are sodium, potassium...
• ionic silver-impregnated sodium carboxymethyl cellulose antimicrobial dressingA textile fiber dressing composed of ionic silver-impregnated sodium carboxymethylcellulose with potential...
• ionizing radiationA type of high-energy radiation that has enough energy to remove an electron (negative particle) from an atom...
• ionomycinAn antibiotic drug used to treat infection.
• iopamidolAn organic iodine compound and used as a non-ionic water soluble radiographic contrast medium. Iopamidol...
• iopromideA contrast medium.
• IORTRadiation treatment aimed directly at a tumor during surgery. Also called intraoperative radiation therapy.
• IOUSA procedure that uses ultrasound (high-energy sound waves that are bounced off internal tissues and organs)...
• IPWithin the peritoneal cavity (the area that contains the abdominal organs). Also called intraperitoneal.
• IP6A substance found in many foods that come from plants, including corn, wheat, rice, and soybeans, and in...
• ipafriceptA proprietary fusion protein comprised of the cysteine-rich domain of frizzled family receptor 8 (Fzd8) fused...
• ipamorelinA pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing...
• iparomlimab/tuvonralimabA mixture of the two engineered monoclonal antibodies iparomlimab, which is an immunoglobulin G4 (IgG4)...
• ipatasertibAn orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential...
• ipilimumabA drug that binds to the protein CTLA-4 to help immune cells kill cancer cells better and is used to treat...
• ipomeanolA natural toxic furan isolated from a fungus-infected sweet potato (Ipomoea batatas) with potential...
• iproplatinA synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and...
• iPSC-derived allogeneic anti-HER2 CAR T cells FT825An off-the-shelf (OTS) preparation of induced pluripotent stem cell (iPSC)-derived, multiplexed-engineered...
• iPSC-derived anti-BCMA CAR/CD16/IL-15RF-expressing CD38-eliminated NK cells FT576An allogeneic, off-the-shelf, natural killer (NK) cell product derived from a clonal master induced...
• iPSC-derived anti-CD19 CAR/CD16/IL-15RF/ADR-expressing CD38-eliminated NK cells FT522An allogeneic, off-the-shelf, natural killer (NK) cell product derived from a clonal master induced...
• iPSC-derived CD16-expressing natural killer cells FT516An allogeneic, off-the-shelf, natural killer (NK) cell product derived from a clonal master induced...
• iPSC-derived CD16/IL-15RF-expressing anti-CD19 CAR-NK cells FT596An allogeneic, off-the-shelf, chimeric antigen receptor (CAR)-natural killer (NK) cell product derived from a...
• iPSC-derived CD16/IL-15RF-expressing CD38-eliminated NK Cells FT538An allogeneic, off-the-shelf, natural killer (NK) cell product derived from a clonal master induced...
• iPSC-derived MSCs CYP-001A preparation of allogeneic mesenchymal stem cells (MSCs) derived from induced pluripotent stem cells...
• iPSC-derived natural killer cells FT500A preparation of off-the-shelf, natural killer (NK) cells derived from a clonal master induced pluripotent...
• ipsilateralOn the same side of the body as another structure or a given point.
• iptacopanAn orally available, small-molecule inhibitor of complement factor B (FB) with potential immunomodulatory...
• iq’mikA type of smokeless tobacco that is made by mixing cured tobacco leaves with ashes from a certain type of...
• iratumumabA fully human monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized...
• IRBA group of scientists, doctors, clergy, and patient advocates that reviews and approves the detailed plan for...
• IRDye800CW-labeled GPC3-targeted agentA fluorescence imaging agent and an immunoconjugate comprised of a glypican 3 (GPC3)-targeting moiety...
• IRDye800CW-labeled heptapeptide KSP-910638GAn imaging agent composed of a heptapeptide targeting human epithelial growth factor receptor type 2 (EGFR2...
• IRDye800CW-nimotuzumabA fluorescence imaging and contrast agent and immunoconjugate comprised of nimotuzumab, a humanized...
• IRDye800-labeled heterodimeric peptide KSP-QRH 919288GA heterodimeric peptide consisting of the heptapeptide monomers KSPNPRF (KSP) and QRHKPRE (QRH) targeting...
• IRE1 RNase inhibitor ORIN1001An orally bioavailable inhibitor of the serine/threonine-protein kinase/endoribonuclease inositol-requiring...
• IressaA drug used to treat non-small cell lung cancer that has spread to other parts of the body and has certain...
• iriduim Ir 192A radioactive isotope of iridium. Iridium-192 emits gamma rays and has a half-life of 74 days. A high dose...
• irinotecan hydrochlorideA drug used alone or with other drugs to treat colorectal cancer that has spread to other parts of the body...
• irinotecan hydrochloride and floxuridine liposome LY01616A liposomal formulation composed of a combination of two antineoplastic agents, the hydrochloride (HCl) salt...
• irinotecan liposome HR070803A liposomal formulation of the semisynthetic camptothecin analogue irinotecan, with potential antineoplastic...
• irinotecan sucrosofateA form of the anticancer drug irinotecan hydrochloride that is contained inside very tiny, fat-like particles...
• irinotecan-eluting beadsMicroporous hydrospheres of polyvinylalcohol (PVA) impregnated with irinotecan with potential antineoplastic...
• irinotecan/P-glycoprotein inhibitor HM30181AK combination tabletAn orally bioavailable combination tablet containing the semisynthetic camptothecin derivative irinotecan and...
• irisThe colored tissue at the front of the eye that contains the pupil in the center. The iris helps control the...
• irofulvenA substance being studied in the treatment of some types of cancer. Irofulven attaches to the cell's DNA and...
• ironAn important mineral the body needs to make hemoglobin, a substance in the blood that carries oxygen from the...
• iron dextran complexA colloidal solution containing ferric oxyhydroxide complexed with polymerized dextran, used as a form of...
• iron isomaltoside 1000An intravenous colloidal solution containing trivalent iron (Fe3+) chelated to isomaltosides, used as iron...
• iron overloadA condition in which the body takes up and stores more iron than it needs. The extra iron is stored in the...
• iron sucrose injectionA sterile aqueous complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Following...
• iron-conjugated polymers in saline suspensionA magnetic tracer composed of a suspension containing iron conjugated to polymers that can potentially be...
• irradiatedTreated with radiation.
• irradiated allogeneic human lung cancer cells expressing OX40L-Ig vaccine HS-130An allogeneic irradiated human lung cancer cell vaccine expressing a fusion protein composed of the OX40...
• irradiationThe use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer...
• irreversible enzyme inhibitorA substance that permanently blocks the action of an enzyme. In cancer treatment, irreversible enzyme...
• irreversible toxicitySide effects that are caused by toxic substances or something harmful to the body and do not go away.
• irrigationIn medicine, washing out an organ (such as the stomach or colon), a body cavity, or a wound by flushing it...
• irritable bowel syndromeA disorder of the intestines commonly marked by abdominal pain, bloating, and changes in a person’s bowel...
• irritable colonA disorder of the intestines commonly marked by abdominal pain, bloating, and changes in a person’s bowel...
• IRS1/IRS2/STAT3 inhibitor NT219An inhibitor of signal transducer and activator of transcription 3 (STAT3) and insulin receptor substrate 1...
• iruplinalkibAn orally available, small molecule inhibitor of the receptor tyrosine kinase (RTK) anaplastic lymphoma...
• Isaac syndromeA rare nerve disorder that causes constant muscle activity that cannot be controlled, even during sleep. It...
• isatuximabA drug used with other drugs to treat adults with certain types of multiple myeloma. It is also being studied...
• isatuximab-irfcA humanized IgG1 monoclonal antibody directed against the cell surface glycoprotein CD-38 with potential...
• isavuconazoleA water-soluble triazole prodrug with broad-spectrum antifungal activity. Administered intravenously or...
• isavuconazonium sulfateThe sulfate ester form of isavuconazonium, a prodrug of the triazole antifungal agent isavuconazole, with...
• ischemiaLack of blood supply to a part of the body. Ischemia may cause tissue damage due to the lack of oxygen and...
• ischemic necrosisA condition in which there is a loss of blood flow to bone tissue, which causes the bone to die. It is most...
• iseganan hydrochlorideA substance being studied in the treatment of oral mucositis (painful mouth sores) caused by cancer therapy...
• ISIS 2503A substance that is being studied in the treatment of cancer.
• ISIS 3521A substance that is being studied in the treatment of cancer.
• ISIS 5132A substance that is being studied in the treatment of cancer.
• islet cellA pancreatic cell that produces hormones (e.g., insulin and glucagon) that are secreted into the bloodstream...
• islet cell carcinomaA rare cancer that forms in islet cells (hormone-making cells) of the pancreas. Islet cells make several...
• islet cell tumorA tumor that forms in islet cells (hormone-making cells) of the pancreas. Islet cell tumors may be benign...
• islet of Langerhans cellA pancreatic cell that produces hormones (e.g., insulin and glucagon) that are secreted into the bloodstream...
• isocitrate dehydrogenase-1 geneA gene that makes a protein that helps break down fats for energy and protect cells from harmful molecules...
• isocitrate dehydrogenase-2 geneA gene that makes a protein that is found inside small structures in cells called mitochondria and that helps...
• isoflavoneAn estrogen-like substance made by some plants, including the soy plant. Soy isoflavones are being studied in...
• iso-fludeloneA third-generation epothilone B analogue with potential anti-mitotic and antineoplastic activites...
• isofluraneA fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of...
• isointenseHaving the same intensity as another object. Used to describe the results of imaging tests, such as x-rays...
• isolated hepatic perfusionA procedure in which a catheter is placed into the artery that provides blood to the liver. A second catheter...
• isolated limb infusionA procedure used to deliver anticancer drugs directly to an arm or leg but not to the rest of the body. The...
• isolated limb perfusionA procedure that may be used to deliver anticancer drugs directly to an arm or leg. The flow of blood to and...
• isolated lung perfusionA surgical procedure during which the circulation of blood to the lungs is separated from the circulation of...
• isolationState of being separated from others. Isolation is sometimes used to prevent disease from spreading.
• isomerOne of two or more compounds that have the same chemical formula but different arrangements of the atoms...
• isoniazidA synthetic derivative of nicotinic acid with anti-mycobacterial properties. Although its mechanism of action...
• isopropyl alcoholAn isomer of propyl alcohol with antibacterial properties. Although the exact mechanism of isopropanol's...
• isoquercetinAn orally bioavailable, glucoside derivative of the flavonoid quercetin and protein disulfide isomerase (PDI)...
• isosulfan blueA dye made in the laboratory that helps identify the sentinel lymph node (the first lymph node that cancer...
• isotopeA form of a chemical element in which the atoms have the same number of protons (part of the nucleus of an...
• isotretinoinA drug closely related to vitamin A that is used to treat severe acne and may also be used to treat other...
• ispinesibA substance being studied in the treatment of cancer. Ispinesib blocks a protein that tumor cells need to...
• ISS 1018 CpG oligodeoxynucleotideA short, synthetic, unmethylated CpG motif-based oligodeoxynucleotide (CpG ODN) with immunostimulatory...
• isthmusA narrow part inside the body that connects two larger structures.
• IstodaxA drug used to treat adults with cutaneous T-cell lymphoma that has already been treated with at least one...
• isunakinraA recombinant protein resembling interleukin-1 (IL-1) receptor antagonist (IL-1Ra), with potential...
• isuventatugA human immunoglobulin G1 (IgG1) monoclonal antibody directed against the natural-killer group 2, member D...
• itacitinib adipateThe adipate salt form of itacitinib, an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1)...
• itacnosertibAn orally bioavailable inhibitor of activin A receptor type 1 (activin receptor-like kinase 2; ALK2; ALK-2...
• ITDA type of genetic change in which a DNA sequence in a gene is copied and inserted right after the original...
• ITK inhibitor CPI-818An orally available, small-molecule, irreversible inhibitor of interleukin-2 inducible T-cell kinase (ITK)...
• ItovebiA drug used with palbociclib and fulvestrant to treat adults with certain types of hormone-receptor positive...
• ITPA condition in which platelets (blood cells that cause blood clots to form) are destroyed by the immune...
• itraconazoleA drug used to prevent or treat fungal infections. It belongs to the family of drugs called antifungal agents.
• itraconazole dispersion in polymer matrixA proprietary oral formulation composed of the poorly soluble, synthetic triazole agent, itraconazole...
• IUA unit used to measure the activity of many vitamins, hormones, enzymes, and drugs. An IU is the amount of a...
• IUDA small, plastic T-shaped device that is placed inside the uterus (the small, hollow, pear-shaped organ in a...
• IVInto or within a vein. IV usually refers to a way of giving a drug or other substance through a needle or...
• ivabradine hydrochlorideThe hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic...
• IVAC mutanome vaccineAn individualized, poly-neo-epitopic encoding, ribonucleic acid (RNA)-based cancer vaccine that targets a...
• ivaltinostatA histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Ivaltinosta tinhibits the...
• ivarmacitinibAn orally available inhibitor of Janus-associated kinase 1 (JAK1), with potential antineoplastic activity...
• ivermectinA macrocyclic lactone derived from Streptomyces avermitilis with antiparasitic activity. Ivermectin exerts...
• IVFA procedure in which eggs are removed from a woman’s ovary and combined with sperm outside the body to form...
• IVIGA substance made from antibodies that have been taken from the blood of many healthy donors. It is given to a...
• ivonescimabA bispecific antibody directed against the negative immunoregulatory human cell receptor programmed cell...
• ivosidenibA drug used alone or with other drugs to treat adults with certain types of acute myeloid leukemia...
• IVPAn x-ray image of the kidneys, ureters, and bladder, and prostate in men, that is taken after a contrast dye...
• IVUAn x-ray image of the kidneys, ureters, and bladder, and prostate in men, that is taken after a contrast dye...
• ivuxolimabAn agonistic antibody that recognizes the co-stimulatory receptor OX40 (CD134; TNFRSF4), with potential...
• IwilfinA drug used to reduce the risk of relapse in adults and children with high-risk neuroblastoma that has gotten...
• ixabepiloneA drug used alone or with capecitabine to treat breast cancer that is locally advanced or has spread to other...
• ixabepilone (oral)An enteric-coated formulation of ixabepilone, a semisynthetic analogue of epothilone B and a non-taxane...
• ixazomib citrateA drug used with lenalidomide and dexamethasone to treat multiple myeloma. It is used in patients who...
• IxempraA drug used alone or with capecitabine to treat breast cancer that is locally advanced or has spread to other...
• ixotatug vedotinAn antibody-drug conjugate (ADC) composed of ixotatug, a humanized monoclonal antibody directed against the...
• izalontamabAn immunoglobulin G (IgG) bispecific antibody targeting both the epidermal growth factor receptor (EGFR...
• izalontamab brengitecanA dual-targeted antibody-drug conjugate (ADC) consisting of a bispecific antibody directed against both the...
• izorlisibAn orally bioavailable inhibitor of the class I phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)...
• izuralimabA humanized, Fc-engineered bispecific monoclonal antibody directed against both the human negative...

791 of 17,721 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.