Oncology and biomedicine terminology · MLC-0111

Oncology and biomedicine terms: T (968)

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• T-LGL leukemiaA type of leukemia in which large T lymphocytes (a type of white blood cell) that contain granules (small...
• TLK286A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
• TLR 2/6/9 agonist PUL-042A solution consisting of a combination of two toll-like receptor (TLR) ligands: Pam2CSK4 acetate (Pam2), a...
• TLR agonist BSG-001A toll-like receptor (TLR) agonist with potential immunomodulating and antineoplastic activities. Upon...
• TLR agonist Decoy20A multi-targeted toll-like receptor (TLR) agonist, with potential immunomodulating and antineoplastic...
• TLR1/2 agonist Pam3Cys-GDPKHPKSFA vaccine adjuvant and synthetic Toll-like receptor (TLR) type 1 and 2 ligand composed of a lipopeptide...
• TLR4 agonist G100A synthetic lipid A derivative and selective toll-like receptor 4 (TLR4) agonist composed of glucopyranosyl...
• TLR4 agonist GSK1795091A toll-like receptor 4 (TLR4) agonist, with potential immunoadjuvant activity. Upon administration...
• TLR7 agonist ANA773 tosylateThe tosylate salt form of ANA773, a Toll-like Receptor 7 (TLR7) agonist prodrug with potential...
• TLR7 agonist APR003An orally bioavailable, small molecule Toll-Like Receptor 7 (TLR7) agonist, with potential immunostimulating...
• TLR7 agonist BNT411A Toll-like receptor (TLR) 7 agonist with potential immunostimulating and antitumor activities. Upon...
• TLR7 agonist CAN1012A Toll-like receptor type 7 (TLR 7) agonist, with potential immunostimulating and antineoplastic activities...
• TLR7 agonist JNJ-64794964An orally bioavailable Toll-like receptor (TLR) 7 agonist, with potential immunostimulating, antiviral and...
• TLR7 agonist LHC165A benzonapthyridine Toll-like receptor (TLR) 7 agonist that is adsorbed to aluminum hydroxide with...
• TLR7 agonist RO7119929An orally bioavailable Toll-like receptor (TLR) 7 agonist, with potential immunostimulating and antitumor...
• TLR7 agonist SHR2150A Toll-like receptor (TLR) 7 agonist with potential immunostimulating and antineoplastic activities. Upon...
• TLR7/8 agonist BM201An extended-release (ER) microparticle formulation of toll-like receptor type 7 and 8 (TLR 7/8) agonist, with...
• TLR7/8 agonist MEDI9197A toll-like receptor type 7 and 8 (TLR7/8) agonist with potential immunostimulating and antitumor activities...
• TLR8 agonist DN1508052A small molecule Toll-like receptor 8 (TLR8; CD288) agonist with potential immunostimulating and...
• TLR9 agonist DUK-CPG-001A synthetic CpG-rich oligonucleotide with potential immunopotentiating activity. TLR9 agonist DUK-CPG-001...
• TLR9 agonist EMD 1201081A synthetic oligonucleotide containing phosphorothioate oligodeoxynucleotide with potential...
• TLR9 agonist IMO-2055A synthetic oligonucleotide containing unmethylated CpG dinucleotides with potential immunopotentiating...
• TLR9 agonist MGN1703A synthetic oligonucleotide based on a proprietary double stem-loop immunomodulator design with potential...
• TLR9 agonist SD-101A proprietary oligonucleotide with immunostimulatory activity. Immunostimulatory phosphorothiolate...
• TLR-directed cationic lipid-DNA complex JVRS-100A cationic lipid DNA complex (CLDC) consisting of DOTIM/cholesterol liposomes and plasmid DNA, containing...
• T-lymphoblastic lymphomaA type of non-Hodgkin lymphoma in which too many T-cell lymphoblasts (immature white blood cells) are found...
• TMA mental technique used to promote relaxation, reduce stress, and improve quality of life. TM is the...
• TM4SF1-CAR/EpCAM-CAR-expressing autologous T cellsA mixed preparation of allogeneic T lymphocytes that have been genetically modified to express either a...
• TMBThe total number of mutations (changes) found in the DNA of cancer cells. Knowing the TMB may help plan the...
• TMC6 geneA gene that makes a protein involved in forming channels through which proteins and other molecules move...
• TMC8 geneA gene that makes a protein involved in forming channels through which proteins and other molecules move...
• TMDA bone marrow disorder that can occur in newborns who have Down syndrome. It is marked by abnormal, immature...
• TMPRSS6 RNAi SLN124An RNA interference (RNAi) therapeutic composed of the liver-targeted ligand N-acetylgalactosamine (GalNAc)...
• TNBCA type of breast cancer in which the tumor cells do not have estrogen receptors, progesterone receptors, or...
• TNFA protein made by white blood cells in response to an antigen (substance that causes the immune system to...
• TNFalpha/IL-2-encoding oncolytic adenovirus TILT-123A genetically-engineered, replication competent, oncolytic serotype 5/3 capsid-modified adenovirus and...
• TNF-bound colloidal goldA substance being studied in the treatment of some types of cancer. TNF-bound colloidal gold is made in the...
• TNFeradeA gene therapy product that is being studied in combination with radiation therapy in the treatment of cancer.
• TNF-related apoptosis-inducing ligandA cell protein that can attach to certain molecules in some cancer cells and may kill the cells. TNF-related...
• TNM staging systemA system to describe the amount and spread of cancer in a patient’s body, using TNM. T describes the size of...
• TNP-470A substance being studied in the treatment of cancer. It may prevent the growth of new blood vessels that...
• TobaccoA plant with leaves that have high levels of the addictive chemical nicotine. After harvesting, tobacco...
• Tobacco tarA chemical substance made when tobacco is burned. Tar contains most of the cancer-causing and other harmful...
• Tobacco-specific nitrosamineA type of harmful, cancer-causing chemical found in tobacco and tobacco smoke. Tobacco-specific nitrosamines...
• TobemstomigA bispecific antibody directed against the human negative immunoregulatory checkpoint receptors programmed...
• Tobramycin sulfateThe sulfate salt of tobramycin, an aminoglycoside antibiotic derived from the bacterium Streptomyces...
• TocilizumabA drug used to treat adults and children aged 2 years and older with severe or life-threatening cytokine...
• TocladesineA substance that has been studied as an anticancer drug. It is an analog of a substance that occurs naturally...
• TocophersolanA water-soluble amphipathic formulation of d-alpha-tocopherol succinate coupled, through a succinate linker...
• TocotrienolAny of the four forms, alpha, beta, gamma and delta, of a member of the vitamin E family, with potential...
• Tocotrienol-rich fractionAn orally available nutritional supplement containing high amounts of the vitamin E family member tocotrienol...
• TofacitinibAn orally available inhibitor of Janus kinases (JAK), with immunomodulatory and anti-inflammatory activities...
• Tofacitinib topical creamA topical cream formulation containing the Janus kinase (JAK) inhibitor tofacitinib, with potential...
• TolakA drug that contains the active ingredient fluorouracil and is used as a cream to treat actinic keratosis (a...
• TolazamideAn intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. Tolazamide is converted...
• TolbutamideA first-generation sulfonylurea with hypoglycemic activity. Tolbutamide binds to and blocks adenosine...
• TolcaponeA benzophenone derivative and a catechol-O-methyltransferase (COMT) inhibitor. Tolcapone selectively and...
• TolebrutinibAn orally bioavailable, brain-penetrant, selective, small molecule inhibitor of Bruton's tyrosine kinase...
• Tolfenamic acidAn orally available, benzoic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with...
• TolinapantAn orally bioavailable, non-peptidomimetic antagonist of both X chromosome-linked inhibitor of apoptosis...
• Toll-like receptor 7 agonist DSP-0509A synthetic, small molecule, toll-like receptor (TLR) 7 agonist, with potential immunostimulatory and...
• Toll-like receptor 7/8 agonist BDB018A toll-like receptor type 7 and 8 (TLR 7/8) agonist, with potential immunostimulating and antitumor...
• TolueneA strong-smelling, colorless liquid used to make gasoline and other types of fuel, paint, paint thinner...
• Tomato-soy juiceA juice containing tomato extract and soy protein with potential chemopreventive and antiproliferative...
• TomivosertibAn orally bioavailable inhibitor of mitogen-activated protein kinase (MAPK)-interacting...
• TomographyA series of detailed pictures of areas inside the body. The pictures are created by a computer linked to an...
• TomotherapyA type of therapy in which radiation is aimed at a tumor from many different directions. The patient lays on...
• TomuzotuximabA glycoengineered second-generation antibody of cetuximab with potential antineoplastic activities. Upon...
• TongaAn herb native to islands in the South Pacific. Substances taken from the root have been used in some...
• Tongue cancerCancer that begins in the tongue. When the cancer begins in the front two-thirds of the tongue, it is...
• TonsilOne of two small masses of lymphoid tissue on either side of the throat.
• TopicalOn the surface of the body.
• Topical AKT inhibitor SM-020A topical gel formulation of an inhibitor of the serine/threonine protein kinase AKT (protein kinase B), with...
• Topical ammonia-oxidizing bacteria-based probiotic solutionA probiotic spray containing a live-cultured strain of ammonia-oxidizing bacteria (AOB), with potential skin...
• Topical betulinic acidA topical formulation of a pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark...
• Topical calcitriolA topical formulation containing the hormonally active form of vitamin D3, with potential protective activity...
• Topical cantharidine solutionA topical, diluted solution composed of the terpenoid cantharidin, which is a natural toxin extracted from...
• Topical celecoxibA topical cream formulation containing celecoxib, a nonsteroidal anti-inflammatory drug (NSAID), with...
• Topical chemotherapyTreatment with anticancer drugs in a lotion or cream applied to the skin.
• Topical cocaine hydrochlorideA topical formulation of the hydrochloride salt of the tropane alkaloid cocaine, with local anesthetic...
• Topical fibrinogen-depleted human standardized platelet lysate CAM-101A topical ophthalmic drop formulation containing fibrinogen-depleted, standardized human platelet lysate...
• Topical fluorouracilA topical formulation containing the antimetabolite 5-fluorouracil (5-FU), with antineoplastic activity. Upon...
• Topical gel HT-001A topical gel formulation, with potential immunomodulatory activity that can potentially be used for...
• Topical gemcitabine hydrochlorideA topical preparation of gemcitabine hydrochloride with antineoplastic activity. Gemcitabine, an analogue of...
• Topical keratinA topical formulation containing the naturally-derived biomaterial keratin that has wound repair-promoting...
• Topical mentholA topical cream containing menthol that both causes a localized cooling sensation and has analgesic...
• Topical myristyl nicotinate creamA topical cream containing the ester prodrug myristyl nicotinate (MN), a lipophilic nicotinic acid derivative...
• Topical naloxone hydrochlorideA topical lotion formulation of the dehydrated, hydrochloride salt form of naloxone, an opiate antagonist...
• Topical Nigella sativa seed oilA topical preparation containing the oil extracted from the seeds of Nigella sativa, also known as black seed...
• Topical phenylephrine solutionA topical solution containing phenylephrine, a sympathomimetic amine with vasoconstricting activity. Upon...
• Topical Piper crocatum extractA topical preparation containing an ethanol extract of Piper crocatum (red betel leaves), with potential...
• Topical piperidine nitroxide MTS-01A topical gel containing a cell permeable hydrophilic piperidine nitroxide with potential radioprotective and...
• Topical potassium dobesilateA topical formulation composed of an inhibitor of fibroblast growth factor (FGF), with potential...
• Topical sirolimusA topical formulation containing the macrolide sirolimus (rapamycin), which is produced by the organism...
• Topical thrombin gelA topical porous, pliable, purified porcine skin gelatin-based pad containing bovine-derived thrombin, with...
• Topical tirbanibulinAn ointment containing an inhibitor for both Src tyrosine kinase and tubulin polymerization, with potential...
• Topical trichloroacetic acidA topical solution containing the caustic agent trichloroacetic acid (TCA), with potential keratolytic...
• Topical VBP-926 solutionA topical solution with potential anti-inflammatory activity. Upon topical application to the affected area...
• Topical vitamin EA topical preparation of the fat-soluble vitamin E with potential antioxidant and cytoprotective activities...
• Topical wound spray HP802-247A cell-based combination product consisting of a fibrinogen solution and a cell preparation containing...
• TopiramateA sulfamate-substituted monosaccharide with anticonvulsant activity. Although the mechanism of action has not...
• Topoisomerase I inhibitor Genz-644282A non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I...
• Topoisomerase I inhibitor LMP400An indenoisoquinoline and non-camptothecin inhibitor of topoisomerase I (Top I) with potential antineoplastic...
• Topoisomerase I inhibitor LMP776An indenoisoquinoline and non-camptothecin inhibitor of topoisomerase I (Top I) with potential antineoplastic...
• Topoisomerase II inhibitorA substance that blocks the activity of the enzyme topoisomerase II, which cuts and repairs tangled strands...
• Topoisomerase II inhibitor RTA 744A substance being studied in the treatment of adult brain tumors. Topoisomerase II inhibitor RTA 744 crosses...
• Topoisomerase I/II inhibitor NEV-801A multi-targeted agent with potential antineoplastic activity. Upon administration, NEV-801 appears to...
• Topoisomerase inhibitorA substance that blocks topoisomerases (enzymes that break and rejoin DNA strands and are needed for cells to...
• Topoisomerase-1 inhibitor LMP744An indenoisoquinoline derivative and topoisomerase 1 (Top1) inhibitor, with potential antineoplastic...
• Topotecan hydrochlorideA drug used alone or with other drugs to treat certain types of ovarian cancer, small cell lung cancer, and...
• Topotecan sustained-release episcleral plaqueAn episcleral plaque containing sustained-release (SR) topotecan, a semisynthetic derivative of camptothecin...
• TopsalysinA targeted prodrug consisting of a recombinant modified form of the Aeromonas protoxin proaerolysin (PA)...
• TORC1/2 kinase inhibitor DS-3078aAn orally bioavailable inhibitor of raptor-mTOR protein complex (TORC1) and rictor-mTOR protein complex...
• Toremifene citrateA drug used to treat postmenopausal women with breast cancer that has spread to other parts of the body. It...
• ToripalimabA drug used alone or with other drugs to treat adults with certain types of nasopharyngeal cancer (a type of...
• Toripalimab-tpziA humanized immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human...
• ToriselA drug used to treat advanced renal cell carcinoma (a type of kidney cancer). It is also being studied in the...
• TORSSurgery in which a robot with arms is used to remove cancer from hard-to-reach areas of the mouth and throat...
• TorsoThe main part of the body that contains the chest, abdomen, pelvis, and back. Most of the body’s organs and...
• Torvutatug samrotecanAn antibody-drug conjugate (ADC) composed of torvutatug, a human monoclonal antibody targeting folate...
• TosedostatA proprietary orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic...
• TositumomabA drug used together with another drug to treat certain types of B-cell non-Hodgkin lymphoma. It is also...
• Tositumomab and iodine I 131 tositumomabA murine IgG2a lambda monoclonal antibody, both unradiolabeled and radiolabeled with iodine I 131, directed...
• TosposertibAn orally bioavailable inhibitor of transforming growth factor-beta (TGFb), with potential antineoplastic and...
• Total androgen blockadeTreatment used to block androgen (male hormone) activity in the body. This may be done by giving an...
• Total estrogen blockadeTherapy used to eliminate estrogen in the body. This may be done with surgery, radiation therapy...
• Total hysterectomySurgery to remove the uterus and the cervix. The ovaries and fallopian tubes may also be removed. A total...
• Total laryngectomyAn operation to remove all of the larynx (voice box).
• Total mastectomySurgery to remove the whole breast, which may include the nipple, areola (the dark-colored skin around the...
• Total nodal irradiationRadiation therapy to the mantle field, the spleen, the lymph nodes in the upper abdomen, and the lymph nodes...
• Total pancreatectomySurgery to remove the entire pancreas. Part of the stomach, part of the small intestine, the common bile...
• Total parenteral nutritionA form of long-term nutritional support that is given directly into the bloodstream through a catheter placed...
• Total PSAThe total amount of prostate-specific antigen (PSA) in the blood. It includes the amount of free PSA and the...
• Total skin electron beam radiation therapyA type of radiation therapy using electrons that is directed at the entire surface of the body. This type of...
• Total tumor mRNA-pulsed tumor-specific ex vivo-expanded autologous lymphocyte transfer cellsA preparation of ex vivo expanded, autologous lymphocyte transfer cells (xALTs) that are loaded with total...
• Total tumor RNA-loaded dendritic cell vaccineA cancer vaccine containing autologous dendritic cells (DCs) that are loaded with total tumor RNA (TTRNA)...
• Total-body irradiationA type of radiation therapy that is given to the entire body. Total-body irradiation is often used with...
• TotectA drug that contains the active ingredient dexrazoxane and is used to treat severe side effects caused by...
• TotipotentHaving to do with cells that are able to develop into any type of cell found in the body.
• TotrombopagAn orally available small molecule agonist of the platelet thrombopoietin (TPO) receptor (TPOR; MPL), with...
• TourniquetA device, such as a strip of cloth or a band of rubber, that is wrapped tightly around a leg or an arm to...
• TovorafenibA drug used to treat children aged 6 months and older with low-grade glioma (a type of brain tumor) that has...
• ToxemiaDisease caused by the spread of bacteria and their toxins in the bloodstream. Also called blood poisoning and...
• ToxicHaving to do with poison or something harmful to the body. Toxic substances usually cause unwanted side...
• ToxicantA poison that is made by humans or that is put into the environment by human activities. Many pesticides are...
• ToxicityThe extent to which something is poisonous or harmful.
• ToxicologyThe study of poisons, including the source, effect, and treatment of poisoning. It is a branch of...
• ToxinA poison made by certain bacteria, plants, or animals, including insects.
• Tozasertib lactateThe lactate salt of tozasertib, a synthetic, small-molecule Aurora kinase inhibitor with potential antitumor...
• TozinameranA formulation consisting of lipid nanoparticle (LNP) encapsulating a nucleoside modified messenger RNA...
• TozuleristideA tumor targeting imaging agent composed of the tumor-specific peptide chlorotoxin (CTX), a 36-amino acid...
• TP-38 immunotoxinA substance being studied in the treatment of brain tumors. It combines a protein that binds to certain tumor...
• TP53 geneA gene that makes a protein that is found inside the nucleus of cells and plays a key role in controlling...
• tPAAn enzyme made in the body that helps dissolve blood clots. A form of this enzyme is made in the laboratory...
• TPFAn abbreviation for a chemotherapy combination used to treat certain types of head and neck cancer and...
• TPF regimenAn abbreviation for a chemotherapy combination used to treat certain types of head and neck cancer and...
• TPI 287A synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and...
• TPNA form of long-term nutritional support that is given directly into the bloodstream through a catheter placed...
• TPOA substance made by the body that helps make blood cells, especially platelets. A form of TPO made in the...
• TPO receptor agonist ONO-7746An orally available small molecule and platelet thrombopoietin (TPO) receptor (TPOR; MPL) agonist with...
• TrabectedinA drug used to treat liposarcoma and leiomyosarcoma (types of soft tissue sarcoma) that cannot be removed by...
• Trabecular cancerA rare type of cancer that forms on or just beneath the skin, usually in parts of the body that have been...
• TrabedersenA transforming growth factor (TGF)-beta2 specific phosphorothioate antisense oligodeoxynucleotide with the...
• TRAC locus integrated anti-CD19 19(T2)28z1xx CAR-T cellsA preparation of T lymphocytes that have been genetically modified to express a chimeric antigen receptor...
• Trace elementAn element found in very small amounts in a given substance. Organisms need certain trace elements to survive.
• TracerA substance (such as a radioisotope) used in imaging procedures.
• Trach tubeA 2-inch- to 3-inch-long curved metal or plastic tube placed in a surgically created opening (tracheostomy)...
• TracheaThe airway that leads from the larynx (voice box) to the bronchi (large airways that lead to the lungs). Also...
• Tracheal carinaA ridge at the base of the trachea (windpipe) that separates the openings of the right and left main bronchi...
• TrachelectomySurgery to remove the cervix. There are two types of trachelectomy: simple trachelectomy and radical...
• Tracheobronchial tumorA tumor that begins in cells that line the trachea (windpipe) or bronchi (large airways of the lung)...
• Tracheoesophageal punctureA small opening made by a surgeon between the esophagus and the trachea. A valve keeps food out of the...
• TracheostomySurgery to create an opening (stoma) into the windpipe. The opening itself may also be called a tracheostomy.
• Tracheostomy buttonA 0.5-inch- to 1.5-inch-long plastic tube placed in a surgically created opening (tracheostomy) in the...
• Tracheostomy tubeA 2-inch- to 3-inch-long curved metal or plastic tube placed in a surgically created opening (tracheostomy)...
• TraditionA belief or behavior that is passed from generation to generation in a family, a culture, or a religion.
• Traditional acupunctureAn ancient form of acupuncture based on the principle that there are five universal elements (wood, fire...
• Traditional Chinese MedicineA medical system that has been used for thousands of years to prevent, diagnose, and treat disease. It is...
• Traditional surrogateA woman who carries and gives birth to a baby for a person who is not able to have children. The woman who is...
• TRAILA cell protein that can attach to certain molecules in some cancer cells and may kill the cells. TRAIL is...
• TRAIL receptor 1A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer...
• TRAIL receptor 2A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer...
• TRAIL-R1A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer...
• TRAIL-R2A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer...
• Trained immunity natural killer cells IBR900A preparation of trained immunity natural killer (tiNK) cells, with potential cytolytic and antineoplastic...
• TRAM flapA type of surgery used to rebuild the shape of the breast after a mastectomy. A muscle in the lower abdomen...
• Tramadol hydrochlorideA drug used to treat moderate to severe pain in adults. It binds to opioid receptors in the central nervous...
• Trametinib dimethyl sulfoxideA drug used alone or with dabrafenib to treat low-grade glioma (a type of brain tumor) in children aged 1...
• Tranexamic acidA synthetic derivative of the amino acid lysine with antifibrinolytic activity. With strong affinity for the...
• TranquilizerA drug that calms and soothes, and reduces stress and tension. Tranquilizers are used to treat anxiety and...
• Trans fatA type of fat that has certain chemical properties and is usually found in processed foods such as baked...
• Trans sodium crocetinateThe sodium salt of the trans-isomer of the carotenoid crocetin with potential antihypoxic and...
• Transabdominal ultrasoundA procedure used to examine the organs in the abdomen. An ultrasound transducer (probe) is pressed firmly...
• TransaminaseA type of enzyme that causes the transfer of a chemical substance called an amino group from one molecule to...
• Transarterial chemoembolizationA procedure in which the blood supply to a tumor is blocked after anticancer drugs are given in blood vessels...
• Transarterial embolizationA procedure in which the blood supply to a tumor or an abnormal area of tissue is blocked. During...
• Transcendental MeditationA mental technique used to promote relaxation, reduce stress, and improve quality of life. Transcendental...
• TransCon IL-2 beta/gammaA hydrogel carrier-based, sustained-release (SR) formulation containing a variant of the endogenous cytokine...
• TranscriptionIn biology, the process by which a cell makes an RNA copy of a piece of DNA. This RNA copy, called messenger...
• Transcription factorOne of a group of proteins that play an important role in controlling the activity of genes. Transcription...
• Transcription factor protein SON-DPA transcription factor (TF) protein, with potential antineoplastic activity. Upon administration, TF protein...
• TranscriptomicsThe study of all RNA molecules in a cell. RNA is copied from pieces of DNA and contains information to make...
• Transcutaneous electrical nerve stimulationA procedure in which mild electric currents are applied to some areas of the skin. Also called TENS.
• TransdermalAbsorbed through the unbroken skin.
• Transdermal 17beta-estradiol gel BHR-200A proprietary, transdermal, hydroalcoholic gel formulation containing 17beta-estradiol, with potential...
• Transdermal 4-hydroxytestosteroneA transdermal formulation containing 4-hydroxytestosterone (4-OHT), a steroidal aromatase inhibitor (AI) and...
• Transdermal estrogenA transdermal formulation containing the synthetic form of estradiol, the most potent, endogenously produced...
• Transfer factorA substance made by some white blood cells. Transfer factor from one person’s white blood cells may be able...
• Transferrin receptor-targeted anti-RRM2 siRNA CALAA-01A proprietary transferrin receptor-targeted nanoparticle preparation of a non-chemically modified...
• Transferrin receptor-targeted liposomal p53 cDNAA cationic liposomal, tumor-targeting p53 (TP53) gene delivery system with potential anti-tumor activity...
• transferrin-CRM107A substance being studied in the treatment of brain tumors. Transferrin-CRM107 is made by linking a...
• TransformationIn medicine, the change that a normal cell undergoes as it becomes malignant.
• Transformation zoneThe area around the opening of the cervix where the endocervix (inner part) and ectocervix (outer part) come...
• TransfusionA procedure in which whole blood or parts of blood are put into a patient’s bloodstream through a vein. The...
• Transgenic lymphocyte immunization vaccineA vaccine consisting of a preparation of allogeneic lymphocytes that encode a gene for telomerase. In...
• Transgenic miceMice that have had DNA from another source put into their DNA. The foreign DNA is put into the nucleus of a...
• Transient abnormal myelopoiesisA bone marrow disorder that can occur in newborns who have Down syndrome. It is marked by abnormal, immature...
• Transient leukemiaA bone marrow disorder that can occur in newborns who have Down syndrome. It is marked by abnormal, immature...
• Transient myeloproliferative disorderA bone marrow disorder that can occur in newborns who have Down syndrome. It is marked by abnormal, immature...
• Transient receptor potential cation channel, subfamily V, member 6A protein found in cell membranes that moves calcium into cells. Levels of transient receptor potential...
• Transitional careSupport given to patients when they move from one phase of disease or treatment to another, such as from...
• Transitional cellA cell that varies in shape depending on whether the tissue is being stretched. Transitional cells may be...
• Transitional cell cancerCancer that begins in cells called urothelial cells that line the urethra, bladder, ureters, renal pelvis...
• TranslationIn biology, the process by which a cell makes proteins using the genetic information carried in messenger RNA...
• Translational researchA term used to describe the process by which the results of research done in the laboratory are used to...
• TranslocationA genetic change in which a piece of one chromosome breaks off and attaches to another chromosome. Sometimes...
• Transoral robotic surgerySurgery in which a robot with arms is used to remove cancer from hard-to-reach areas of the mouth and throat...
• Transperineal biopsyA procedure in which a sample of tissue is removed from the prostate for examination under a microscope. The...
• Transperineal template-guided prostate mapping biopsyA procedure being studied in the diagnosis of prostate cancer and in planning prostate cancer treatment...
• Transplant surgeonA surgeon who has special training in transplantation surgery. The surgeon replaces a patient's organ with an...
• TransplantationA surgical procedure in which tissue or an organ is transferred from one area of a person’s body to another...
• Transrectal biopsyA procedure in which a sample of tissue is removed from the prostate using a thin needle that is inserted...
• Transrectal ultrasoundA procedure in which a probe that sends out high-energy sound waves is inserted into the rectum. The sound...
• Transsphenoidal surgeryA type of surgery in which instruments are inserted through the nose and sphenoid sinus (a hollow space in a...
• Transurethral biopsyA procedure in which a sample of tissue is removed from the prostate for examination under a microscope. A...
• Transurethral electroevaporation of the prostateA procedure used to treat benign prostatic hypertrophy (BPH). An instrument is inserted through the urethra...
• Transurethral electrovaporization of the prostateA procedure used to treat benign prostatic hypertrophy (BPH). An instrument is inserted through the urethra...
• Transurethral incision of the prostateA procedure used to treat benign prostatic hypertrophy (BPH). An instrument is inserted through the urethra...
• Transurethral microwave thermotherapyA procedure used to treat benign prostatic hypertrophy (BPH). An instrument is inserted through the urethra...
• Transurethral needle ablationA procedure that is used to treat benign prostatic hypertrophy (BPH). An instrument with a small probe that...
• Transurethral radiofrequency ablationA procedure that is used to treat benign prostatic hypertrophy (BPH). An instrument with a small probe that...
• Transurethral resectionSurgery performed with a special instrument inserted through the urethra. Also called TUR.
• Transurethral resection of the prostateSurgery to remove tissue from the prostate using an instrument inserted through the urethra. Also called TURP.
• Transvaginal sonographyA procedure used to examine the vagina, uterus, fallopian tubes, ovaries, and bladder. An instrument is...
• Transvaginal ultrasoundA procedure used to examine the vagina, uterus, fallopian tubes, ovaries, and bladder. An instrument is...
• Transverse rectus abdominis myocutaneous flapA type of surgery used to rebuild the shape of the breast after a mastectomy. A muscle in the lower abdomen...
• TranylcypromineAn orally bioavailable, nonselective, irreversible, non-hydrazine inhibitor of both monoamine oxidase (MAO)...
• Tranylcypromine sulfateThe sulfate salt form of tranylcypromine, an orally bioavailable, nonselective, irreversible, non-hydrazine...
• TrastuzumabA drug used alone or with other drugs to treat certain types of breast cancer, stomach cancer, and...
• Trastuzumab and hyaluronidaseA combination of two drugs used alone or with other drugs to treat adults with certain types of HER2-positive...
• Trastuzumab and hyaluronidase-oyskA ready-to-use combination of trastuzumab, a recombinant humanized monoclonal antibody directed against the...
• Trastuzumab botidotinAn antibody-drug conjugate (ADC) composed of trastuzumab, a humanized monoclonal antibody targeting human...
• Trastuzumab conjugate BI-CON-02A conjugated form of trastuzumab, a humanized monoclonal antibody directed against the human epidermal growth...
• Trastuzumab deruxtecanA drug used to treat adults with certain types of HER2-positive or HER2-low breast cancer, HER2-positive...
• Trastuzumab duocarmazineAn antibody-drug conjugate (ADC) composed of the recombinant humanized anti-epidermal growth factor receptor...
• Trastuzumab imbotolimodAn immune stimulating antibody conjugate (ISAC) consisting of trastuzumab, an anti-human epidermal growth...
• Trastuzumab rezetecanAn antibody-drug conjugate (ADC) composed of trastuzumab, a humanized immunoglobulin G1-kappa (IgG1k)...
• Trastuzumab vedotinAn antibody-drug conjugate (ADC) composed of trastuzumab, a humanized immunoglobulin G1 (IgG1) monoclonal...
• Trastuzumab/tesirine antibody-drug conjugate ADCT-502An antibody-drug conjugate (ADC) consisting of an engineered version of the humanized monoclonal anti-human...
• TraumaInjury to the body, or an event that causes long-lasting mental or emotional damage.
• Traumeel SA substance that contains minerals and extracts of 14 plants, including belladonna, arnica, St. John's wort...
• TrazimeraA drug used alone or with other drugs to treat certain types of breast cancer, stomach cancer, and...
• TrazodoneA drug used to treat depression. It may also be used to help relieve anxiety and insomnia (trouble sleeping)...
• TreandaA drug used to treat chronic lymphocytic leukemia and certain types of non-Hodgkin lymphoma. It is also being...
• Treatment courseA treatment plan made up of several cycles of treatment. For example, treatment given for one week followed...
• Treatment cycleA period of treatment followed by a period of rest (no treatment) that is repeated on a regular schedule. For...
• Treatment fieldIn radiation therapy, the place on the body where the radiation beam is aimed.
• Treatment planA detailed plan with information about a patient’s disease, the goal of treatment, the treatment options for...
• Treatment scheduleA step-by-step plan of the treatment that a patient is going to receive. A treatment schedule includes the...
• Treatment summaryA detailed summary of a patient’s disease, the type of treatment the patient received, and any side effects...
• TrebananibAn angiopoietin (Ang) 1 and 2 neutralizing peptibody, with potential antiangiogenic activity. Trebananib...
• Treg inhibitor GIM-531An orally bioavailable small molecule inhibitor of regulatory T-cells (Tregs), with potential...
• T-regulatory cellA type of immune cell that blocks the actions of some other types of lymphocytes, to keep the immune system...
• T-regulatory cell-enriched donor cellsA preparation of donor-derived T cells that have been enriched with donor T-regulatory (Treg) cells, with...
• TrelstarA drug used to treat advanced prostate cancer. It is also being studied in the treatment of other types of...
• TremelimumabA drug that binds to the protein CTLA-4 to help immune cells kill cancer cells better and is used to treat...
• Tremelimumab-actlA human IgG2 monoclonal antibody directed against the T-cell receptor protein cytotoxic...
• Tremtelectogene empogeditemcelA preparation of allogeneic, human leukocyte antigen (HLA) matched, cluster of differentiation 34...
• TreosulfanA drug given with fludarabine phosphate before a donor hematopoietic stem cell transplant in adults and...
• TrephineA surgical tool used to cut out circular pieces of bone or other tissue.
• TretinoinA nutrient that the body needs in small amounts to function and stay healthy. Tretinoin is made in the body...
• TrexallA drug used alone or with other drugs to treat many types of cancer, certain types of arthritis, and severe...
• TriacetyluridineA drug used in the emergency treatment of adults and children who receive too much fluorouracil or...
• Trial sponsorA person, company, institution, group, or organization that oversees or pays for a clinical trial and...
• TriamcinoloneA substance that is being studied for the prevention of nonmelanoma skin cancer. It is an anti-inflammatory...
• Triamcinolone acetonideThe acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and...
• Triamcinolone acetonide transdermal system SUN-131A transdermal system (TDS) containing triamcinolone acetonide, a synthetic glucocorticoid with...
• TriapineA substance being studied in the treatment of cancer. It is a type of ribonucleotide reductase inhibitor...
• TriazinateA synthetic dihydrotriazine derivative with antineoplastic properties. As an antifolate agent related to...
• Triazine derivative TriN2755A synthetic triazene derivative with antineoplastic activity. Upon metabolic activation via N-demethylation...
• TributyrinA triglyceride drug that may inhibit cell growth and induce cell differentiation. Differentiating agents may...
• TricaprinAn orally available precursor of decanoic acid (DA), a 10-carbon fatty acid and major component of medium...
• TrichilemmomaA benign (not cancer) tumor that begins in the outer cells of a hair follicle and appears as a small, smooth...
• Trichostatin AA natural derivative of dienohydroxamic acid isolated from species of the bacterial genus Streptomyces...
• TrichothiodystrophyA rare, inherited genetic disorder marked by short, dry hair that breaks easily and has a light- and...
• Triciribine phosphateThe phosphate salt of the synthetic, cell-permeable tricyclic nucleoside triciribine with potential...
• Triclosan/copolymer/fluoride toothpasteA fluoride-based toothpaste containing the anti-inflammatory and broad-spectrum antibacterial agent triclosan...
• TriCorA drug used to treat high levels of cholesterol and triglycerides in the blood. TriCor is being studied in...
• Tricyclic antidepressantA type of drug used to treat depression.
• Trientine hydrochlorideThe hydrochloride salt form of a metal chelating agent with potential anti-angiogenic activity. Trientine...
• Trifluoperazine hydrochlorideThe hydrochloride salt of trifluoperazine, a phenothiazine derivative and a dopamine, alpha-adrenergic, and...
• TrifluridineA fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA...
• Trifluridine and tipiracil hydrochlorideA combination of two drugs used alone or with bevacizumab to treat adults with certain types of colorectal...
• Trifolium pratenseA plant whose flowers have been used in some cultures to treat certain medical problems. It is being studied...
• Trigeminal nerveThe main sensory nerve of the head and face, and the motor nerve of the muscles used in chewing. Also called...
• TriggerIn medicine, a specific event that starts a process or that causes a particular outcome. For example...
• Trigger point acupunctureUse of acupuncture to treat pain by inserting needles into trigger points on the body. Trigger points are...
• TrigriluzoleA formulation comprised of a prodrug form of the benzothiazole derivative riluzole, with potential...
• TriiodothyronineA thyroid hormone. Also called T-3.
• TrilaciclibA small molecule, competitive inhibitor of cyclin dependent kinases 4 and 6 (CDK4/6), with potential...
• TrilisateA substance used to treat arthritis and relieve pain, inflammation, and fever. It is also being studied in...
• TrilostaneA synthetic derivative of androstane with adrenocortical suppressive properties. Trilostane reversibly...
• Trimeric GITRL-Fc OMP-336B11A Fc-engineered human fusion protein composed of two trimers of tumor necrosis factor (ligand) superfamily...
• TrimetazidineAn orally available small molecule compound with anti-ischemic, and potential immunomodulating and...
• Trimethoprim-sulfamethoxazoleAn antibiotic drug used to treat infection and prevent pneumocystis carinii pneumonia.
• Trimethylcolchicinic acidA colchicine analog with potential antineoplastic activity. Trimethylcolchicinic acid binds to tubulin...
• Trimetrexate glucuronateA drug that belongs to the family of drugs called antimetabolites. It is used in the treatment of...
• Trinucleotide repeatA sequence of three nucleotides that is repeated a number of times in a row in a segment of DNA. A certain...
• TriostatA drug that is used to treat certain thyroid (a gland located near the voice box) conditions. It is also...
• Triple-negative breast cancerA type of breast cancer in which the tumor cells do not have estrogen receptors, progesterone receptors, or...
• Triple-positive breast cancerA type of breast cancer in which the tumor cells have estrogen receptors, progesterone receptors, and a...
• Triptolide analogA water soluble analog of the diterpenoid triepoxide triptolide isolated from the Chinese herb Tripterygium...
• TriptorelinA synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater...
• Triptorelin pamoateA drug used to treat advanced prostate cancer. It is also being studied in the treatment of other types of...
• Tris-acryl gelatin microspheresAn embolic particle composed of water-soluble, compressible, nonabsorbable tris-acryl gelatin microspheres...
• TrisenoxA drug used to treat acute promyelocytic leukemia that has a certain chromosome abnormality or a fusion gene...
• TrisomyThe presence of three copies of a specific chromosome in some or all of the body’s cells instead of the usual...
• Trisomy 18A genetic disorder caused by having an extra chromosome 18 in some or all of the body’s cells. Trisomy 18 is...
• Trisomy 21A genetic condition caused by having an extra chromosome 21 in some or all of the body’s cells. Trisomy 21 is...
• Tri-specific NK cell engager CC-92328A tri-specific natural killer (NK) cell engager, with potential immunomodulating and antineoplastic...
• Trivalent influenza vaccineA synthetic vaccine consisting of three inactivated influenza viruses, two different influenza type A strains...
• Trivalent live-attenuated influenza vaccineA weakened live virus vaccine containing three seasonal influenza reassortants with prophylactic activity...
• tri-virus/GD2-specific allogeneic cytotoxic T-lymphocytesAllogeneic tri-viral specific, Epstein-Barr virus (EBV), cytomegalovirus (CMV) and adenovirus (Ad), cytotoxic...
• TRK inhibitor AZD6918An orally available liquid suspension containing the tropomyosin receptor kinase (Trk) inhibitor AZD6918 with...
• Trk inhibitor LOXO-101A drug used to treat adults and children with certain types of solid tumors that have spread or cannot be...
• TRK inhibitor LOXO-195An orally bioavailable, selective tropomyosin-related-kinase (tyrosine receptor kinase; TRK) inhibitor, with...
• TRK inhibitor TQB3558An orally available inhibitor of tropomyosin receptor kinase (Trk), with potential antineoplastic activity...
• TRK inhibitor TQB3811An orally bioavailable inhibitor of tropomyosin receptor kinase (TRK), with potential antineoplastic...
• TRK inhibitor VC004An orally bioavailable, second-generation tropomyosin-related-kinase (TRK) inhibitor, with potential...
• TRK protein familyA family of proteins that are found on nerve cells. They are involved in cell signaling pathways that control...
• TrkA inhibitor VMD-928An orally bioavailable, selective inhibitor of tropomyosin receptor kinase A (TrkA; neurotrophic tyrosine...
• TRK/RET inhibitor ND-003An orally bioavailable small molecule inhibitor of multiple kinases, including tropomyosin-related-kinase...
• TRK/ROS1/ALK inhibitor SIM1803-1AAn orally available inhibitor of multiple kinases, including the receptor tyrosine kinase anaplastic lymphoma...
• TrodelvyA drug used to treat adults with certain types of breast cancer that have already been treated with other...
• TrodusquemineA naturally-occurring cholestane and non-competitive, allosteric inhibitor of protein tyrosine phosphatase 1B...
• TrofosfamideAn orally bioavailable oxazaphosphorine prodrug with antineoplastic activity. Trofosfamide (TFF) is...
• TroglitazoneAn orally-active thiazolidinedione with antidiabetic and hepatotoxic properties and potential antineoplastic...
• TrophoblastA thin layer of cells that helps a developing embryo attach to the wall of the uterus, protects the embryo...
• TropisetronA drug used to prevent nausea and vomiting caused by cancer treatment. It is also used to prevent nausea and...
• Tropisetron hydrochlorideThe hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3...
• Tropomyosin receptor kinase protein familyA family of proteins that are found on nerve cells. They are involved in cell signaling pathways that control...
• TrotabresibAn orally bioavailable inhibitor of the Bromodomain and Extra-Terminal (BET) family of proteins, with...
• TrovostobartAn engineered, human immunoglobulin (Ig) G1 monoclonal antibody directed against the negative immune...
• TroxacitabineA drug being studied for use as an anticancer agent.
• Troxacitabine nucleotide prodrug MIV-818A liver-targeting nucleotide phosphoramidate prodrug of troxacitabine monophosphate (TRX-MP), a dioxolane...
• TRP2 mRNA-electroporated autologous langerhans-type dendritic cell vaccineA cancer cell vaccine composed of autologous human Langerhans-type dendritic cells (also known as Langerhans...
• TRPV6A protein found in cell membranes that moves calcium into cells. Levels of TRPV6 are lower than normal in...
• TRPV6 calcium channel inhibitor SOR-C13An inhibitor of transient receptor potential cation channel vanilloid family member 6 (TRPV6, CaT1 or CATL)...
• True histiocytic lymphomaA rare, very aggressive (fast-growing) type of non-Hodgkin lymphoma (cancer that begins in the cells of the...
• True lavenderA plant with aromatic leaves and flowers that is a member of the mint family. Oil from the flowers has been...
• Truncated tissue factor/NGR peptideA vascular-targeting agent composed of the extracellular domain of the trunctated form of issue factor (tTF)...
• TrunkThe main part of the body that contains the chest, abdomen, pelvis, and back. Most of the body’s organs and...
• TruqapA drug used with fulvestrant to treat adults with hormone-receptor positive, HER2-negative breast cancer that...
• TRUSA procedure in which a probe that sends out high-energy sound waves is inserted into the rectum. The sound...
• TrustA legal document in which a person states what is to be done with his or her property after death. There are...
• TruximaA drug that contains the active ingredient rituximab and is used alone or with other drugs to treat adults...
• TryptophanaseEncoded by human TDO2 Gene, 406-aa 48-kDa Tryptophanase is a homotetramer that may bind protoheme IV involved...
• TSEB radiation therapyA type of radiation therapy using electrons that is directed at the entire surface of the body. This type of...
• TSHA hormone produced by the pituitary gland. TSH stimulates the release of thyroid hormone from thyroglobulin...
• TSNAA type of harmful, cancer-causing chemical found in tobacco and tobacco smoke. TSNAs are formed when tobacco...
• TSP-1 activator VT1021A cyclic pentapeptide and stimulator of thrombospondin 1 (TSP-1; THBS1), with potential anti-angiogenic...
• TSP-1 mimetic fusion protein CVX-045A fusion protein containing two thrombospondin (TSP-1)-derived nonamer peptides covalently attached, via a...
• TTI-237A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called...
• TTK/PLK1 inhibitor BAL0891An inhibitor of threonine tyrosine kinase (TTK; monopolar spindle 1 kinase; Mps1) and polo-like kinase 1...
• TTMBA procedure being studied in the diagnosis of prostate cancer and in planning prostate cancer treatment...
• TTPThe length of time from the date of diagnosis or the start of treatment for a disease until the disease...
• Tubal ligationAn operation to tie the fallopian tubes closed. This procedure prevents pregnancy by blocking the passage of...
• TubefeedingA way of giving medicines and liquids, including liquid foods, through a small tube placed through the nose...
• TubercidinAn antibiotic and adenosine analog isolated from the bacterium Streptomyces tubercidicus with potential...
• TuberculosisA disease caused by a specific type of bacteria that spreads from one person to another through the air...
• Tuberous sclerosisA genetic disorder in which tumors form in the kidneys, brain, eyes, heart, lungs, and skin. This disease can...
• TubulinOne of a group of proteins found in high levels in the cell cytoplasm (fluid inside a cell but outside the...
• Tubulin inhibitor ALB 109564(a)A semi-synthetic derivative of the vinka alkaloid vinblastine with potential antineoplastic activity. Tubulin...
• Tubulin inhibitor-containing antibody-drug conjugateAny antibody-drug conjugate (ADC) that contains a tubulin inhibitor as the cytotoxic payload.
• Tubulin polymerization inhibitor AB8939A small molecule tubulin polymerization inhibitor with potential antineoplastic activity. Upon...
• Tubulin-binding agent SSR97225An antimitotic tubulin-binding agent with potential antineoplastic activity. Tubulin-binding agent SSR97225...
• Tubulovillous adenomaA type of polyp that grows in the colon and other places in the gastrointestinal tract and sometimes in other...
• TucatinibA drug used with other drugs to treat adults with certain types of HER2-positive breast cancer or certain...
• TucidinostatAn orally bioavailable benzamide-type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10, with...
• Tucotuzumab celmoleukinA recombinant fusion protein comprised of a human monoclonal antibody directed against the epithelial cell...
• TUEVAPA procedure used to treat benign prostatic hypertrophy (BPH). An instrument is inserted through the urethra...
• Tufted angiomaA rare, benign (not cancer) blood vessel tumor that usually forms on the skin of the arms and legs, but may...
• Tui naChinese massage that uses kneading, pressing, rolling, shaking, and stretching of the body. Tui na is thought...
• TUIPA procedure used to treat benign prostatic hypertrophy (BPH). An instrument is inserted through the urethra...
• TukysaA drug used with other drugs to treat adults with certain types of HER2-positive breast cancer or certain...
• TulmimetostatAn orally available selective inhibitor of the histone lysine methyltransferase (HMT) enhancer of zeste...
• Tumescent mastectomyA type of surgery to remove the breast. The breast is injected with a liquid mixture of salts and small...
• TumorAn abnormal mass of tissue that forms when cells grow and divide more than they should or do not die when...
• Tumor antigen vaccineA vaccine made of cancer cells, parts of cancer cells, or pure tumor antigens (substances isolated from tumor...
• Tumor board reviewA treatment planning process in which a group of cancer doctors and other health care specialists meet...
• Tumor burdenRefers to the number of cancer cells, the size of a tumor, or the amount of cancer in the body. Also called...
• Tumor debulkingSurgical removal of as much of a tumor as possible. Tumor debulking may increase the chance that chemotherapy...
• Tumor DNA sequencingA laboratory method used to learn the exact order (sequence) of the chemical building blocks that make up...
• Tumor gradeA description of a tumor based on how abnormal the cancer cells and tissue look under a microscope and how...
• Tumor heterogeneityA term that describes the differences between tumors of the same type in different patients, the differences...
• Tumor initiationA process in which normal cells are changed so that they are able to form tumors. Substances that cause...
• Tumor loadRefers to the number of cancer cells, the size of a tumor, or the amount of cancer in the body. Also called...
• Tumor lysis syndromeA condition that can occur after treatment of a fast-growing cancer, especially certain leukemias and...
• Tumor markerA substance found in tissue, blood, bone marrow, or other body fluids that may be a sign of cancer or certain...
• Tumor marker testA test that measures the amount of substances called tumor markers in tissue, blood, urine, or other body...
• Tumor microenvironmentThe normal cells, molecules, and blood vessels that surround and feed a tumor cell. A tumor can change its...
• Tumor modelCells, tissues, or animals used to study the development and progression of cancer, and to test new...
• Tumor mutational burdenThe total number of mutations (changes) found in the DNA of cancer cells. Knowing the tumor mutational burden...
• Tumor necrosis factorA protein made by white blood cells in response to an antigen (substance that causes the immune system to...
• Tumor necrosis factor ligand superfamily member 10Tumor necrosis factor ligand superfamily member 10 (281 aa, ~33 kDa) is encoded by the human TNFSF10 gene...
• Tumor necrosis factor receptor superfamily member 10AA protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer...
• Tumor necrosis factor receptor superfamily member 10BA protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer...
• Tumor necrosis factor-related apoptosis-inducing ligandA cell protein that can attach to certain molecules in some cancer cells and may kill the cells. Tumor...
• Tumor peptide-loaded myeloid dendritic cellsA cell-based cancer vaccine composed of myeloid dendritic cells (myDCs) pulsed with tumor peptides with...
• Tumor profilingA laboratory method that checks for the presence of certain genes, proteins, or other molecules in a sample...
• Tumor promotionA process in which existing tumors are stimulated to grow. Tumor promoters are not able to cause tumors to...
• Tumor protein p53 geneA gene that makes a protein that is found inside the nucleus of cells and plays a key role in controlling...
• Tumor suppressor geneA type of gene that makes a protein called a tumor suppressor protein that helps control cell growth...
• Tumor vasculature-targeted tumor necrosis factor alphaA substance being studied in the treatment of cancer. It is made by linking tumor necrosis factor (TNF) to a...
• Tumor volumeThe size of a cancer measured by the amount of space taken up by the tumor. For example, the tumor volume of...
• Tumor-agnostic therapyA type of therapy that uses drugs or other substances to treat cancer based on the cancer’s genetic and...
• Tumor-cells apoptosis factor hormone-peptideA synthetic 14-amino acid peptide derived from a novel human peptide hormone, Tumor-Cells Apoptosis Factor...
• Tumor-derivedTaken from an individual's own tumor tissue; may be used in the development of a vaccine that enhances the...
• Tumor-infiltrating lymphocyteA type of immune cell that has moved from the blood into a tumor. Tumor-infiltrating lymphocytes can...
• Tumor-infiltrating lymphocyte therapyA type of treatment in which tumor-infiltrating lymphocytes (a type of immune cell that can recognize and...
• Tumor-specific antigenA protein or other molecule that is found only on cancer cells and not on normal cells. Tumor-specific...
• TUMTA procedure used to treat benign prostatic hypertrophy (BPH). An instrument is inserted through the urethra...
• TUNAA procedure that is used to treat benign prostatic hypertrophy (BPH). An instrument with a small probe that...
• TunlametinibAn orally bioavailable inhibitor of mitogen-activated protein kinase kinase (MAP2K, MAPK/ERK kinase, or MEK)...
• TURSurgery performed with a special instrument inserted through the urethra. Also called transurethral resection.
• TuralioA drug used to treat adults with tenosynovial giant cell tumor (a rare, usually benign tumor that affects the...
• Turcot syndromeA rare, inherited disorder in which polyps (abnormal growths of tissue) form on the inside walls of the colon...
• Turkish rhubarbThe root of this plant has been used in some cultures to treat certain medical problems. It may have...
• TurmericAn East Indian plant that is a member of the ginger family and is used as a spice and food color. It is a...
• Turner syndromeA genetic condition that occurs in females who have a missing or abnormal X chromosome (sex chromosome)...
• TURPSurgery to remove tissue from the prostate using an instrument inserted through the urethra. Also called...
• Tusamitamab ravtansineAn immunoconjugate consisting of anti-carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5)...
• TUVPA procedure used to treat benign prostatic hypertrophy (BPH). An instrument is inserted through the urethra...
• TuvusertibAn orally available inhibitor of ataxia telangiectasia and Rad3 related (ATR) kinase, with potential...
• T-VECA drug used to treat melanoma that has recurred (come back) after surgery. It is used in patients whose...
• TVSA procedure used to examine the vagina, uterus, fallopian tubes, ovaries, and bladder. An instrument is...
• Twelve-step programA program to help people recover from substance abuse, emotional disorders, or addictions. The twelve steps...
• Ty21a typhoid vaccineA live attenuated bacteria oral vaccine used to prevent typhoid, which is caused by Salmonella typhi.
• TykerbA drug used with capecitabine or letrozole to treat certain types of HER2-positive breast cancer that are...
• TympanitesSwelling of the abdomen caused by gas in the intestines or peritoneal cavity. Also called meteorism.
• Type 2 diabetes mellitusA disease in which glucose levels in the blood are higher than normal because the body does not make enough...
• Type 3 serotonin receptor antagonistA type of drug used to treat certain types of irritable bowel syndrome and relieve nausea and vomiting. It is...
• Type C thymomaA rare type of thymus gland cancer. It usually spreads, has a high risk of recurrence, and has a poor...
• type-1 polarized dendritic cell-induced antigen-specific autologous cytotoxic T lymphocytesA preparation of autologous cytotoxic T lymphocytes (CTL), specifically reactive to melanoma-associated...
• Typhoid vaccineA bacterial vaccine used to prevent typhoid fever, which is caused by Salmonella typhi bacteria.
• TYR geneA gene that makes a protein involved in making melanin (a pigment that gives color to the skin, hair, and...
• TyroserleutideA tripeptide consisting of tyrosine, serine, and leucine with potential antineoplastic activity. Although the...
• Tyrosinase peptideA protein that is made from tumor cells and is used in a vaccine against melanoma. A tyrosinase peptide...
• Tyrosinase-related protein-1A recombinant peptide of the tyrosinase-related protein 1 (TRP1) used in vaccine therapy. Expressed by cells...
• Tyrosine kinase inhibitorA substance that blocks the action of enzymes called tyrosine kinases. Tyrosine kinases are a part of many...
• Tyrosine kinase inhibitor BIBF 1120A substance being studied in the treatment of some types of cancer. Tyrosine kinase inhibitor BIBF 1120...
• Tyrosine kinase inhibitor IDRX-42An orally bioavailable small molecule inhibitor of an as of yet undisclosed tyrosine kinase, with potential...
• Tyrosine kinase inhibitor OSI-930A selective thiophene-derived tyrosine kinase inhibitor with potential antineoplastic activity. Tyrosine...
• Tyrosine kinase inhibitor TL-895An orally bioavailable inhibitor of tyrosine kinase, with potential anti-inflammatory and antineoplastic...
• Tyrosine kinase inhibitor XL228A synthetic molecule that targets multiple tyrosine kinases with potential antineoplastic activity. Tyrosine...
• TyrosinemiaA rare, inherited disorder marked by high blood levels of a protein building block called tyrosine. This can...
• TYRP1 geneA gene that makes a protein involved in making melanin (a pigment that gives color to skin, hair, and eyes)...
• TZT-1027A substance being studied in the treatment of cancer. It is a type of tubulin inhibitor. Also called...

968 of 17,717 terms in Oncology and biomedicine terminology (MLC-0111). Request the full dataset.